Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
On Nonlinear Integral Inequalities of Gronwall Type in Two Variables [PDF]
In this paper we obtain some new nonlinear integral inequality of Gronwall type involving functions of two independent variables which can be used in the analysis of the behavior of the solutions of some partial differential ...
Kim, Young-Ho, Dragomir, Sever S
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Numerical methods for nonlinear partial differential equations of fractional order [PDF]
In this article, we implement relatively new analytical techniques, the variational iteration method and the Adomian decomposition method, for solving nonlinear partial differential equations of fractional order.
Odibat, Zaid, Momani, Shaher
core +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
A Class of Quasilinear Equations with Riemann–Liouville Derivatives and Bounded Operators
The existence and uniqueness of a local solution is proved for the incomplete Cauchy type problem to multi-term quasilinear fractional differential equations in Banach spaces with Riemann–Liouville derivatives and bounded operators at them.
Vladimir E. Fedorov +2 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
PRIN 2009: Critical point theory and perturbative methods for nonlinear differential equations. Hamiltonian Systems and Partial Differential Equations [PDF]
Many partial differential equations arising in Physics can be seen as innite dimensional Hamiltonian systems. Main examples are the nonlinear Schrodinger (NLS) and wave (NLW) equations, the beam, membrane and Kirkhoff equations in elasticity theory, the ...
BERTI, MASSIMILIANO
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Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
In the present article we investigate problems of tracking in the moving point control of thermal processes described by Fredholm integro-differential equations in partial derivatives with the Fredholm integral operator, in the case when the functions ...
A. Kerimbekov +2 more
doaj +1 more source
Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham +14 more
wiley +1 more source

