Results 51 to 60 of about 9,068 (293)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

On the solvability of the tracking problem in the optimization of the thermal process by moving point controls

Қарағанды университетінің хабаршысы. Математика сериясы, 2021
In the present article we investigate problems of tracking in the moving point control of thermal processes described by Fredholm integro-differential equations in partial derivatives with the Fredholm integral operator, in the case when the functions ...
A. Kerimbekov, A.T. Ermekbaeva, E. Seidakmat kyzy   +2 more
doaj   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Background/Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs Rheumatoid Arthritis (VARA) Registry.
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

An Analytical Technique to Solve the System of Nonlinear Fractional Partial Differential Equations

, 2019
The Kortweg–de Vries equations play an important role to model different physical phenomena in nature. In this research article, we have investigated the analytical solution to system of nonlinear fractional Kortweg–de Vries, partial ...
Muhammad Arif, Hassan Khan, Poom Kumam, Rasool Shah   +3 more
core   +1 more source

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

International Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir, Sarah Mechhoud, Taous‐Meriem Laleg‐Kirati   +2 more
wiley   +1 more source

THE AUTOMODEL SOLUTIONS OF COMPLEX VALUED NONLINEAR DIFFERENTIAL EQUATION IN PARTIAL DERIVATIVES

Вестник Северо-Кавказского федерального университета, 2022
The aim of this article is to find the automodel solutions of nonlinear equation in partial derivatives with the complex valued function. The system of equations, which equivalent to the observable model, is examined at the beginning of the article. The modification of the system to the type, which allows to get the automodel solutions, is shown.
openaire   +1 more source

The generalized Kudryashov method for the nonlinear fractional partial differential equations with the beta-derivative

Revista Mexicana de Física, 2020
In this article, we consider the exact solutions of the Hunter-Saxton and Schrödinger equations defined by Atangana's comformable derivative using the general Kudryashov method. Firstly, Atangana's comformable fractional derivative and its properties are included.
openaire   +1 more source

Solving Some Derivative Equations Fractional Order Nonlinear Partials Using the Some Blaise Abbo Method

Journal of Mathematics Research, 2021
In this paper, we propose the solution of some nonlinear partial differential equations of  fractional order that modeled diffusion, convection and reaction problems. For the solution of these equations we will use the SBA method which is a method based on the combination of the Adomian Decomposition Method (ADM), the Picard's ...
Abdoul wassiha NEBIE, Frederic BERE, Bakari ABBO, Youssouf PARE   +3 more
openaire   +2 more sources