Results 51 to 60 of about 22,994 (260)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Statistical extraction of process zones and representative subspaces in fracture of random composite [PDF]

, 2012
We propose to identify process zones in heterogeneous materials by tailored statistical tools. The process zone is redefined as the part of the structure where the random process cannot be correctly approximated in a low-dimensional deterministic space ...
Bordas, Stephane Pierre-Alain, Kerfriden, Pierre, Rabczuk, Timon, Schmidt, Karl Michael   +3 more
core   +3 more sources

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Exact controllability for nonlocal semilinear differential inclusions

Bruno Pini Mathematical Analysis Seminar
In this paper, we investigate the controllability of a class of semilinear differential inclusions in Hilbert spaces. Assuming the exact controllability of the associated linear problem, we establish sufficient conditions for achieving the exact ...
Irene Benedetti, Angelica Palazzoni
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

The integrability of Lie-invariant geometric objects generated by ideals in the Grassmann algebra

, 1997
We investigate closed ideals in the Grassmann algebra serving as bases of Lie-invariant geometric objects studied before by E. Cartan. Especially, the E.
Ambrose N., Blackmore D., Chevalley C., Holod P.I., Langer J., Loos H.G., Prykarparsky A.K., Prykarpatsky A., Prykarpatsky A.K., Ricca R.L., Sulanke R., Van Groesen E.   +11 more
core   +1 more source

A Comparative Review of Dimension Reduction Methods in Approximate Bayesian Computation [PDF]

, 2013
Approximate Bayesian computation (ABC) methods make use of comparisons between simulated and observed summary statistics to overcome the problem of computationally intractable likelihood functions.
Blum, M. G. B., Nunes, M. A., Prangle, D., Sisson, S. A.   +3 more
core   +4 more sources

Inhomogeneities in Glass: From Defects to Functional Nanostructures

Encyclopedia
Glass inhomogeneities represent variations in the structural or compositional uniformity of glass, traditionally associated with process-related defects such as striae, bubbles, stones, and inclusions that impair transparency and mechanical stability ...
Georgiy Yu. Shakhgildyan, Michael I. Ojovan   +1 more
doaj   +1 more source

Effect of Ductile Damage Evolution in Sheet Metal Forming: Experimental and Numerical Investigations [PDF]

, 2010
The numerical simulation based on the Finite Element Method (FEM) is widely used in academic institutes and in the industry. It is a useful tool to predict many phenomena present in the classical manufacturing forming processes such as necking, fracture,
Abbassi, Fethi, Mistou, Sébastien, Pantalé, Olivier, Rakotomalala, Roger, Zghal, Ali   +4 more
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source