Results 31 to 40 of about 22,994 (260)
Mathematical modelling of the elastic behavior of structured geophysical media
Article is retracted From the viewpoint of modern concepts of nonlinear geophysics, the presence of the hierarchical block structure, anisotropy and heterogeneities is the defining property of the natural medium in particular of the Earth’s crust.
N. V. Olali +2 more
doaj +1 more source
Controllability for systems governed by semilinear evolution equations without compactness [PDF]
We study the controllability for a class of semilinear differential inclusions in Banach spaces. Since we assume the regularity of the nonlinear part with respect to the weak topology, we do not require the compactness of the evolution operator generated
Benedetti, Irene +2 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Modelling of Phase Separation in Alloys with Coherent Elastic Misfit
Elastic interactions arising from a difference of lattice spacing between two coherent phases can have a strong influence on the phase separation (coarsening) of alloys.
Fratzl, P., Lebowitz, J. L., Penrose, O.
core +2 more sources
Nonlinear second-order multivalued boundary value problems [PDF]
In this paper we study nonlinear second-order differential inclusions involving the ordinary vector $p$-Laplacian, a multivalued maximal monotone operator and nonlinear multivalued boundary conditions.
Gasinski, Leszek +1 more
core +2 more sources
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Nonlinear Volterra integrodifferential evolution inclusions and optimal control [PDF]
Volterra integrodifferential evolution inclusions of nonconvolutory type with time dependent unbounded operators and with both convex and nonconvex multivalued perturbations are studied. The results obtained are applied to distributed parameter optimal control problems. By assuming suitable assumptions on the operator \(A\) and on the multifunction \(F\
openaire +3 more sources
Nonlinear Volterra delay evolution inclusions subjected to nonlocal initial conditions
This paper deals with a nonlinear Volterra delay evolution inclusion subjected to a nonlocal implicit initial condition. The evolution inclusion involves an $m$-dissipative operator (possibly multivalued and/or nonlinear) and a noncompact interval. We first consider the evolution inclusion subjected to a local initial condition and prove an existence ...
Yu, Yang-Yang +2 more
openaire +2 more sources
Evolutionary Oseen model for generalized Newtonian fluid with Multivalued Nonmonotone Friction Law [PDF]
The paper deals with the non-stationary Oseen system of equations for the generalized Newtonian incompressible fluid with multivalued and nonmonotone frictional slip boundary conditions.
Dudek, Sylwia, Migórski, Stanisław
core +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source

