Results 51 to 60 of about 423,487 (329)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Analysis of Complex Typography Modulating on Internal Wave's Generation and Propagation [PDF]

open access: yesXibei Gongye Daxue Xuebao, 2018
We use a non-hydrostatic numerical simulation based on incompressible Navier-Stokes equations to model the generation and evolution of nonlinear internal waves formed as a result of the interaction with double-ridge topography.

doaj   +1 more source

Transcritical flow of a stratified fluid over topography: analysis of the forced Gardner equation [PDF]

open access: yes, 2013
Transcritical flow of a stratified fluid past a broad localised topographic obstacle is studied analytically in the framework of the forced extended Korteweg--de Vries (eKdV), or Gardner, equation.
Clift, R.   +7 more
core   +3 more sources

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

open access: yesArthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai   +12 more
wiley   +1 more source

Dynamics of Internal Tides Over a Shallow Ridge Investigated With a High‐Resolution Downscaling Regional Ocean Model

open access: yesGeophysical Research Letters, 2018
This study investigates the dynamics of tidally induced internal waves over a shallow ridge, the Izu‐Ogasawara Ridge off the Japanese mainland, using a downscaled high‐resolution regional ocean numerical model.
Eiji Masunaga   +3 more
doaj   +1 more source

Spectral methods for internal waves: indistinguishable density profiles and double-humped solitary waves [PDF]

open access: yesNonlinear Processes in Geophysics, 2011
Internal solitary waves are widely observed in both the oceans and large lakes. They can be described by a variety of mathematical theories, covering the full spectrum from first order asymptotic theory (i.e.
M. Dunphy, C. Subich, M. Stastna
doaj   +1 more source

Lie Group Analysis of a Nonlinear Coupled System of Korteweg-de Vries Equations

open access: yesEuropean Journal of Mathematical Analysis, 2021
In this paper, we consider coupled Korteweg-de Vries equations that model the propagation of shallow water waves, ion-acoustic waves in plasmas, solitons, and nonlinear perturbations along internal surfaces between layers of different densities in ...
Joseph Owuor Owino, Benard Okelo
doaj   +1 more source

Evidence of multimodal structure of the baroclinic tide in the Strait of Gibraltar [PDF]

open access: yes, 2006
The multimodal structure of the baroclinic tides in the Strait of Gibraltar is studied using observations and numerical simulations. Observational data and model results revealed the presence of two types of tidal internal waves generated over Camarinal ...
Bruno, M   +5 more
core   +2 more sources

Hybrid Auxetic Architectures: Integrating Curvature‐Driven Design for Enhanced Mechanical Tunability and Structural Performance

open access: yesAdvanced Engineering Materials, EarlyView.
Curvature‐tuned auxetic lattices are designed, fabricated, and mechanically characterized to reveal how geometric curvature governs stretchability, stress redistribution, and Poisson's ratio evolution. Photoelastic experiments visualize stress pathways, while hyperelastic simulations quantify deformation mechanics.
Shuvodeep De   +3 more
wiley   +1 more source

From Luzon Strait to Dongsha Plateau: Stages in the Life of an Internal Wave [PDF]

open access: yesOceanography, 2011
Tidal currents in Luzon Strait south of Taiwan generate some of the largest internal waves anywhere in the ocean. Recent collaborative efforts between oceanographers from the United States and Taiwan explored the generation, evolution, and ...
David M. Farmer   +5 more
doaj  

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