Results 51 to 60 of about 519,710 (307)

Identification of Industrial Furnace Temperature for Sintering Process in Nuclear Fuel Fabrication Using NARX Neural Networks

open access: yesScience and Technology of Nuclear Installations, 2014
Nonlinear system identification is becoming an important tool which can be used to improve control performance and achieve robust fault-tolerant behavior.
Dede Sutarya, Benyamin Kusumoputro
doaj   +1 more source

Identification of Nonlinear Latent Hierarchical Models

open access: yes, 2023
Identifying latent variables and causal structures from observational data is essential to many real-world applications involving biological data, medical data, and unstructured data such as images and languages. However, this task can be highly challenging, especially when observed variables are generated by causally related latent variables and the ...
Kong, Lingjing   +5 more
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

System identification using neuro fuzzy approach for IoT application

open access: yesMeasurement: Sensors, 2022
The Internet of Things (IoT) has become a popular application in recent years. However, it is the wireless communication mode. In such a scenario, the user would have to send information either nonlinear or dynamic data type in the form of a signal or an
Rakesh Kumar Pattanaik   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Recursive bayesian identification of nonlinear autonomous systems [PDF]

open access: yes, 2012
This paper concerns the recursive identification of nonlinear discrete-time systems for which the original equations of motion are not known. Since the true model structure is not available, we replace it with a generic nonlinear model.
Barão, Miguel   +2 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Identification of High-Order Nonlinear Coupled Systems Using a Data-Driven Approach

open access: yesApplied Sciences
Most works related to the identification of mathematical nonlinear systems suggest that such approaches can always be directly applied to any nonlinear system. This misconception is greatly discouraging when the obtained results are not expected.
Rodolfo Daniel Velázquez-Sánchez   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Dynamic Modeling of Electric Power on Light UAV

open access: yesJournal of Harbin University of Science and Technology, 2020
Focused on UAV(unmanned aerial vehicle) equipped electric power plant composed by Electric speed controllers, brushless DC motors and fixpitched propellers, a modeling method combined deduction with identification is studied Firstly, in consideration of ...
AN Siqi   +3 more
doaj   +1 more source

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