Results 71 to 80 of about 430,734 (311)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
, 2017 In this paper, deterministic and stochastic SEIRI epidemic models featuring a distributed latent period and general, unspecified nonlinear incidence and growth rates for the susceptible class are proposed and investigated from a stability viewpoint.
Xia, Juan, Zhang, Hong, Georgescu, Paul
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Asset allocation and regime switching on Croatian financial market
Croatian Operational Research Review, 2016 It has been known for quite some time now that financial markets exhibit changes in regimes over time. A majority of the literature tends to support that financial markets undergo regimes of bull and bear markets. This characteristic should be modeled in
Tihana Škrinjarić, Boško Šego
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Tropical Medicine and Infectious Disease, 2018 Modelling dengue fever in endemic areas is important to mitigate and improve vector-borne disease control to reduce outbreaks. This study applied artificial neural networks (ANNs) to predict dengue fever outbreak occurrences in San Juan, Puerto Rico (USA)
Abdiel E. Laureano-Rosario +7 more
doaj +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Nonlinear cointegration and nonlinear error correction [PDF]
, 1996 The relationships between stochastic trending variables given by the concepts of cointegration and error correction (EC) are well characterized in a linear context, but the extension to a nonlinear context is still a challenge.
Escribano, Álvaro, Mira, Santiago
core
InformationThis study presents an innovative approach to predicting the water level in the San Juan River, Chocó, Colombia, by implementing two hybrid models: nonlinear auto-regressive with exogenous inputs (NARX) and long short-term memory (LSTM).
Jackson B. Renteria-Mena +1 more
doaj +1 more source
Novel Modelling Approaches to Characterize and Quantify Carryover Effects on Sensory Acceptability
Foods, 2018 Sensory biases caused by the residual sensations of previously served samples are known as carryover effects (COE). Contrast and convergence effects are the two possible outcomes of carryover.
Damir Dennis Torrico +5 more
doaj +1 more source