Results 51 to 60 of about 430,734 (311)

A Non-Linear Continuous-Time Generalized Predictive Control for a Planar Cable-Driven Parallel Robot

Actuators, 2021
This paper addresses a novel nonlinear algorithm for the trajectory tracking of a planar cable-driven parallel robot. In particular, we outline a nonlinear continuous-time generalized predictive control (NCGPC). The proposed controller design is based on
Fouad Inel, Ali Medjbouri, Giuseppe Carbone   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Reduction of nonlinear models for control applications

, 2013
A systematic approach to the model reduction of high-fidelity fluid-structure-flight models and the subsequent flight control design for very flexible aircraft is considered. The test case is for an unmanned aerial vehicle.
Da Ronch, A., Tantaroudas, N. D., Badcock, K. J.   +2 more
core   +1 more source

Optimal design for additive partially nonlinear models [PDF]

, 2010
We develop optimal design theory for additive partially nonlinear regression models, showing that Bayesian and standardized maximin D-optimal designs can be found as the products of the corresponding optimal designs in one dimension.
D. C. Woods, Dette, H., Woods, D. C., Dette, Holger, H. Dette, Woods, David C., Biedermann, S., Woods, D.C., S. Biedermann, Biedermann, Stefanie   +9 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Applications of Artificial Intelligence in Water Resources Forecasting

EDIS
The advent of artificial intelligence (AI) and machine learning has permeated every aspect of our lives. Water resource management is becoming increasingly important due to the impacts of climate change and human activities.
Golmar Golmohammadi, Seyed Mostafa Biazar, Rohith Reddy Nedhunuri, Nikolaos Tziolas   +3 more
doaj   +1 more source

Models nonlinear by parameters

Comput. Sci. J. Moldova, 1997
A combination of Newton's method and the method of shortest downhill is proposed to solve a system of nonlinear algebraic equations with nonlinear parameters.
E. Livovsky, N. Andronaty
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Structurally Site-Aware Parametric Models Improve Cross-Site DBH and Volume Prediction from UAV Laser Scanning (ULS)

Remote Sensing
Reliable estimation of tree-level diameter at breast height (DBH) and stem volume from remote sensing data remains challenging across structurally heterogeneous plantation forests due to cross-site domain shift.
Mark Jayson B. Felix, Michael S. Watt, Sadeepa Jayathunga, Nicolò Camarretta, Robin J. L. Hartley   +4 more
doaj   +1 more source

Estimation of lactation curves of Gyr cattle and some associated production parameters in the Colombian low tropic

Revista Colombiana de Ciencias Pecuarias, 2021
Background: The Gyr breed is widely used in Colombian low tropic dairy production systems. During the last 10 years, the Asociación Colombiana de Criadores de Ganado Cebú† - ASOCEBU, has been leading a dairy milk control program which led to the creation
Daniela Ferro, Jhon Gil, Ariel Jiménez, Carlos Manrique, Carlos A. Martínez   +4 more
doaj   +1 more source