Results 41 to 50 of about 44,204 (309)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Intermediate Models in Nonlinear Optics [PDF]
SIAM Journal on Mathematical Analysis, 2005 This paper deals with models for the simulation of the propagation of laser pulses in a nonlinear medium. The new model turns out to be exact in linear cases, but take into account the nonlinear effects; some numerical results are presented to illustrate the error bounds and to investigate the numerical effectivity of the model.
Thierry Colin +2 more
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Ultrafast nonlinear optics in semiconductors [PDF]
, 1993 The nonlinear optical phenomena which occur in semiconductor materials on a femtosecond to picosecond timescale have recently generated much interest, especially in the field of telecommunications where the development of all-optical switching devices ...
Walmsley, M., Walmsley, M
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Multi-μJ 12 μm Femtosecond GaSe-based OPCPA at 1 kHz Repetition Rate [PDF]
EPJ Web of Conferences, 2022 Fuertjes Pia +4 more
doaj +1 more source
Voltage-driven beam bistability in a reorientational uniaxial dielectric
APL Photonics, 2016 We report on voltage controlled bistability of optical beams propagating in a nonlocal reorientational uniaxial dielectric, namely, nematic liquid crystals. In the nonlinear regime where spatial solitons can be generated, two stable states are accessible
Armando Piccardi +4 more
doaj +1 more source
Nonlinear Optics and Applications [PDF]
, 2007 Nonlinear optics is the result of laser beam interaction with materials and started with the advent of lasers in the early 1960s. The field is growing daily and plays a major role in emerging photonic technology.
Frazier, Donald O. +1 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source
Unifying attoclock and Larmor measurements through position-resolved weak values
Communications PhysicsThe measurement of tunneling times in strong-field ionization has been the topic of much controversy in recent years, with the attoclock and Larmor clock being two of the main contenders for correctly reproducing these times.
Pablo M. Maier +3 more
doaj +1 more source