Results 21 to 30 of about 14,462 (263)

Dynamical behavior analysis and traveling wave solution of stochastic Riemann wave equations

Alexandria Engineering Journal
In this paper, our main purpose is to study dynamical behavior analysis and traveling wave solution of stochastic Riemann wave equations in quantum mechanics.
Jie Luo, Jiangtao Guo, Yan Shao, Guangxu Zhao, Min Jiao   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Qualitative Analysis and Traveling Wave Solutions of a (3 + 1)- Dimensional Generalized Nonlinear Konopelchenko-Dubrovsky-Kaup-Kupershmidt System

Fractal and Fractional
This article investigates the qualitative analysis and traveling wave solutions of a (3 + 1)-dimensional generalized nonlinear Konopelchenko-Dubrovsky-Kaup-Kupershmidt system.
Zhao Li, Ejaz Hussain
doaj   +1 more source

Exact Solutions of Nonlinear Second-Order Autonomous Ordinary Differential Equations: Application to Mechanical Systems

Dynamics, 2023
Many physical processes can be described via nonlinear second-order ordinary differential equations and so, exact solutions to these equations are of interest as, aside from their accuracy, they may reveal beforehand key properties of the system’s ...
Murillo V. B. Santana
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Phase portraits and optical soliton solutions of coupled nonlinear Maccari systems describing the motion of solitary waves in fluid flow

Results in Physics, 2022
The coupled nonlinear Maccari systems are very important equations which have been developed vigorously in the fields of the nonlinear optics, deep water theory, plasma physics, nonlinear optics and so on.
Zhao Li, Xinyu Xie, Changjiang Jin
doaj   +1 more source

Perturbations of nonlinear systems of ordinary differential equations

Journal of Mathematical Analysis and Applications, 1984
Along with the n dimensional system (1) \(y'=f(t,y)\) the perturbed system (2) \(x'=f(t,x)+g(t,x)\) is considered. Certain refined assumptions are made about estimates of the fundamental matrix solution of the variational system with respect to a solution of system (1), and about g. (The function g need not be ''small'', it may be sublinear or linear.)
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Qualitative Analysis of a Retarded Mathematical Framework with Applications to Living Systems

Abstract and Applied Analysis, 2013
This paper deals with the derivation and the mathematical analysis of an autonomous and nonlinear ordinary differential-based framework. Specifically, the mathematical framework consists of a system of two ordinary differential equations: a logistic ...
Carlo Bianca, Massimiliano Ferrara, Luca Guerrini   +2 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source