Results 41 to 50 of about 159,062 (288)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Free Convection Flow and Heat Transfer of Nanofluids of Different Shapes of Nano-Sized Particles over a Vertical Plate at Low and High Prandtl Numbers [PDF]

open access: yesJournal of Applied and Computational Mechanics, 2019
In this paper, free convection flow and heat transfer of nanofluids of differently-shaped nano-sized particles over a vertical plate at very low and high Prandtl numbers are analyzed.
Gbeminiyi Sobamowo
doaj   +1 more source

Symmetries of nonlinear ordinary differential equations: the modified Emden equation as a case study

open access: yes, 2015
Lie symmetry analysis is one of the powerful tools to analyze nonlinear ordinary differential equations. We review the effectiveness of this method in terms of various symmetries. We present the method of deriving Lie point symmetries, contact symmetries,
Chandrasekar, V. K.   +2 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

On one nonlinear integral boundary value problem

open access: yesНауковий вісник Ужгородського університету. Серія: Математика і інформатика, 2017
We give a new approach for the investigation of existence and construction of an approximate solutions of nonlinear non-autonomous systems of ordinary differential equations under nonlinear integral boundary conditions.
Я. В. Варга
doaj   +1 more source

Feedback Stabilization Methods for the Numerical Solution of Systems of Ordinary Differential Equations [PDF]

open access: yes, 2008
In this work we study the problem of step size selection for numerical schemes, which guarantees that the numerical solution presents the same qualitative behavior as the original system of ordinary differential equations, by means of tools from ...
Ch. Tsitouras   +4 more
core   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

On non-oscillation for two dimensional systems of non-linear ordinary differential equations

open access: yesMiskolc Mathematical Notes
The paper studies the non-oscillatory properties of two-dimensional systems of non-linear differential equations u′=g(t)|v|1αsgnv,v′=−p(t)|u|αsgnu,g:[0,+∞[→[0,+∞[p:[0,+∞[→ℝα>0∫+∞g(s ...
Zdeněk Opluštil
doaj   +1 more source

Numerical Simulation of the Nonlinear Fractional Dynamical Systems with Fractional Damping for the Extensible and Inextensible Pendulum

open access: yesJournal of Algorithms & Computational Technology, 2007
In this paper we consider a class of nonlinear dynamical systems with fractional damping. The problem is transformed into a system of fractional-order differential equations.
C. Yin, F. Liu, V. Anh
doaj   +1 more source

Some basic properties of infinite dimensional Hamiltonian systems [PDF]

open access: yes, 1974
We consider some fundamental properties of infinite dimensional Hamiltonian systems, both linear and nonlinear. For exemple, in the case of linear systems, we prove a symplectic version of the teorem of M. Stone.
Chernoff, P. R., Marsden, J. E.
core   +1 more source

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