Results 31 to 40 of about 190,765 (284)

Constructing single-entry stem volume models for four economically important tree species of Greece

open access: yesFolia Oecologica, 2021
Three different nonlinear regression models were tested for their ability to predict stem volume for economically important native tree species in Greece.
Koulelis Panagiotis P., Ioannidis Kostas
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Springback Coefficient Research of API X60 Pipe with Dent Defect

open access: yesEnergies, 2018
Dent is a common form of defect on oil and gas pipeline. Some dents will undergo elastic or plastic recovery due to changes in internal pressure, also known as springback.
Peng Zhang, Yunfei Huang, Ying Wu
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Investigation of Hazelnut Husk Combustion by using A Novel Non-linear Kinetic Model through Thermogravimetric Analysis

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2021
Considering economic and environmental issues, boosting renewable energy source is the main subject to fulfill energy demand in these days. Biomass as natural and abundant energy source can be typically used to produce electricity, fuels and heat ...
Senem Sezer, Uğur Özveren
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Improved methods for the analysis of circadian rhythms in correlated gene expression data [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2018
Circadian clocks regulate biological behaviours, such as sleeping and waking times, that recur naturally on an approximately 24-hour cycle. These clocks tend to be influenced by a variety of external factors, sometimes to the extent that it can have an
Wannapa Pukdee   +2 more
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Impact of mulching and planting time on spring-wheat (Triticum aestivum) growth: A combined field experiment and empirical modeling approach

open access: yesOpen Agriculture
This study aimed to assess the effect of straw-mulching and sowing time on spring-wheat growth and also evaluate the suitability of nonlinear models (Logistic, Gompertz, Richards and Weibull models) in forecasting crop growth.
Alhassan Abdul-Rauf Malimanga
doaj   +1 more source

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