Results 31 to 40 of about 599,650 (333)

A note on the maximum likelihood estimator in the gamma regression model [PDF]

open access: yesOpuscula Mathematica, 2009
This paper considers a nonlinear regression model, in which the dependent variable has the gamma distribution. A model is considered in which the shape parameter of the random variable is the sum of continuous and algebraically independent functions. The
Jerzy P. Rydlewski
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Chanter model: nonlinear modeling of the fruit growth of cocoa [PDF]

open access: yesCiência Rural
: The growth of plants and animals can be described through a growth curve. This curve is given by the equation of a nonlinear model, such as the Logistic model and the Gompertz model. The objective of this study was to adjust the Chanter model, as well
Pollyane Vieira da Silva   +1 more
doaj   +2 more sources

Linearization of randomly weighted empiricals under long range dependence with application to nonlinear regression quantiles [PDF]

open access: yes, 2000
This paper discusses some asymptotic uniform linearity results of randomly weighted empirical processes based on long range dependent random variables+ These results are subsequently used to linearize nonlinear regression quantiles in a nonlinear ...
Mukherjee, Kanchan
core  

Privileged Communications-Attorney and Client [PDF]

open access: yes, 1952
A high-dimensional regression space usually causes problems in nonlinear system identification.However, if the regression data are contained in (or spread tightly around) some manifold, thedimensionality can be reduced.
Glad, Torkel   +3 more
core   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Data Science for Weather Impacts on Crop Yield

open access: yesFrontiers in Sustainable Food Systems, 2020
Private businesses in sectors, such as food, energy, and retail, as well as public sector and federal agencies are interested in the predictive understanding of weather impacts on crop yield, which is an important aspect of food security.
Venkata Shashank Konduri   +3 more
doaj   +1 more source

Optimal designs for a class of nonlinear regression models [PDF]

open access: yes, 2004
For a broad class of nonlinear regression models we investigate the local E- and c-optimal design problem. It is demonstrated that in many cases the optimal designs with respect to these optimality criteria are supported at the Chebyshev points, which ...
Dette, Holger   +2 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Springback Coefficient Research of API X60 Pipe with Dent Defect

open access: yesEnergies, 2018
Dent is a common form of defect on oil and gas pipeline. Some dents will undergo elastic or plastic recovery due to changes in internal pressure, also known as springback.
Peng Zhang, Yunfei Huang, Ying Wu
doaj   +1 more source

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