Results 41 to 50 of about 68,110 (309)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Geometrically Nonlinear Static Analysis of High-Aspect-Ratio Truss-Braced Wing
Engineering ProceedingsTruss-braced wings (TBWs) feature higher aspect ratios with a lighter weight and lower bending moment than conventional wings. These wings show significant potential for performance improvements in terms of fuel efficiency.
Yanxin Huang, Jinchi Chen, Qingyuan Ma
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Analysis of equations arising in gyrotron theory
, 2012 The gyrotron is a microwave source whose operation is based on the stimulated cyclotron radiation of electrons oscillating in a static magnetic field. Powerful gyrotrons can be used to heat nuclear fusion plasma.
Kalis, Harijs +4 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Non-Linear Static Analysis of Masonry Buildings under Seismic Actions [PDF]
Journal of Systemics, Cybernetics and Informatics, 2018 Assessing existing masonry buildings in seismic zones is a critical issue, due to the high vulnerability of the built environment. Commonly, beside local analysis, refined assessment procedures are used based on non-linear static methods, like the ...
Maria Luisa Beconcini +5 more
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Archives of Civil Engineering, 2012 The goal of this work is to compare different constitutive models in the nonlinear static characteristic analysis of asphalt concrete core dams. The Duncan E- μ model, Duncan E-B model and double-yield-surface model are three major constitutive models in
Hong Z., Hongyan Z., Jianke D.
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A Nonlinear Static Procedure for the Seismic Design of Symmetrical Irregular Bridges
Shock and Vibration, 2020 Displacement-based seismic design methods support the performance-based seismic design philosophy known to be the most advanced seismic design theory. This paper explores one common type of irregular-continuous bridges and studies the prediction of their
Shanshan Li +4 more
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Nonlinear Seismic Performance of RC Structures with Different Floor by Capacity Spectrum Method [PDF]
Journal of Structural and Construction Engineering, 2019 Civil engineering structures as well as office or apartment building are affected by earthquakes. In some buildings, few or no walls are provided at the first story (pilot).
علی کارگران, Ali Kheyroddin
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Hysteresis Envelope Model of Double Extended End-Plate Bolted Beam-to-Column Joint
Buildings, 2021 In this study, a hysteresis envelope mathematical model for the double extended end-plate bolted beam-to-column joint is proposed. The aim of a proposed joint model is to provide a more realistic behaviour of steel frames under seismic loading by using ...
Paulina Krolo, Davor Grandić
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source