Results 41 to 50 of about 367,641 (251)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Geometrically Nonlinear Static Analysis of High-Aspect-Ratio Truss-Braced Wing
Engineering ProceedingsTruss-braced wings (TBWs) feature higher aspect ratios with a lighter weight and lower bending moment than conventional wings. These wings show significant potential for performance improvements in terms of fuel efficiency.
Yanxin Huang, Jinchi Chen, Qingyuan Ma
doaj +1 more source
Assessment of Accuracy the Nonlinear Static Analysis in Determining Behavior Factor Reinforced Concrete Moment-Resisiting Frames [PDF]
Journal of Structural and Construction Engineering, 2015 Common methods analysis and design of structures are based according to elastic analysis and and reduction of earthquake forces. This reduction design load in the codes is done by the behavior factors.
Alireza Habibi, Reza gholami
doaj
Nonlocal Strain Gradient Model for the Nonlinear Static Analysis of a Circular/Annular Nanoplate
Micromachines, 2023 A nonlinear static analysis of a circular/annular nanoplate on the Winkler–Pasternak elastic foundation based on the nonlocal strain gradient theory is presented in the paper.
Mostafa Sadeghian +2 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Non-Linear Static Analysis of Masonry Buildings under Seismic Actions [PDF]
Journal of Systemics, Cybernetics and Informatics, 2018 Assessing existing masonry buildings in seismic zones is a critical issue, due to the high vulnerability of the built environment. Commonly, beside local analysis, refined assessment procedures are used based on non-linear static methods, like the ...
Maria Luisa Beconcini +5 more
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Archives of Civil Engineering, 2012 The goal of this work is to compare different constitutive models in the nonlinear static characteristic analysis of asphalt concrete core dams. The Duncan E- μ model, Duncan E-B model and double-yield-surface model are three major constitutive models in
Hong Z., Hongyan Z., Jianke D.
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A Nonlinear Static Procedure for the Seismic Design of Symmetrical Irregular Bridges
Shock and Vibration, 2020 Displacement-based seismic design methods support the performance-based seismic design philosophy known to be the most advanced seismic design theory. This paper explores one common type of irregular-continuous bridges and studies the prediction of their
Shanshan Li +4 more
doaj +1 more source
Nonlinear phononic crystals based on chains of disks alternating with toroidal structures [PDF]
, 2011 We study experimentally the acoustic response of a load-bearing, phononic crystal composed of alternating steel disks, and polytetrafluoroethylene o-rings under precompression.
Brown, M. +3 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source