Results 31 to 40 of about 350,611 (269)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
LPV-Based Controller Design of a Floating Piston Pneumatic Actuator
Actuators, 2020 The paper presents the modeling and control design of a floating piston pneumatic gearbox actuator using a grid-based Linear Parameter Varying approach. First, the nonlinear model of the pneumatic actuator is presented, then it is transformed into a 6th ...
Ádám Szabó +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Manufacturing Review, 2023 In this paper, a new algorithm developing to solve optimization problems with many nonlinear factors in ultra-precision machining by magnetic liquid mixture.
Duc Le Anh +2 more
doaj +1 more source
Observability of nonlinear systems [PDF]
Mathematica Bohemica, 2006 Summary: Observability of a general nonlinear system -- given in terms of an ODE \(\dot {x}=f(x)\) and an output map \(y=c(x)\) -- is defined as in linear system theory (i.e.\,if \(f(x)=Ax\) and \(c(x)=Cx\)). In contrast to standard treatment of the subject we present a criterion for observability which is not a generalization of a known linear test ...
openaire +2 more sources
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Fusion Particle Filter for Nonlinear Systems Based on Segmental Gauss-Hermite Approximation
IEEE Access, 2020 Multisensor fusion estimators play an important role in modern information processing. Weighted measurement fusion (WMF) algorithm has widely been applied to data compression of multisensor linear systems.
Yun Li
doaj +1 more source
Systems of nonlinear wave equations with nonlinear viscosity [PDF]
Pacific Journal of Mathematics, 1988 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Friedman, Avner, Nečas, Jindřich
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Iterated Orthogonal Simplex Cubature Kalman Filter and Its Applications in Target Tracking
Applied Sciences, 2023 In order to increase a nonlinear system’s state estimate precision, an iterated orthogonal simplex cubature Kalman filter (IOSCKF) is presented in this study for target tracking.
Zhaoming Li +3 more
doaj +1 more source