Results 31 to 40 of about 18,411,452 (302)

Carbon market price prediction in the Yangtze River Basin based on improved deep learning ensemble model with CEEMDAN and Attention-RNN

open access: yesCarbon Balance and Management
Accurate carbon price prediction can help the government establish an effective and stable carbon trading market mechanism, which researchers are increasingly focusing on.
Zuliang Lu   +4 more
doaj   +1 more source

The research of river basin ecological compensation based on water emissions trading mechanism

open access: yesWater Science and Technology
By integrating the successful case of the European Union emissions trading system, this study proposes a water emissions trading system, a novel method of reducing water pollution.
Zuliang Lu   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Observability of nonlinear systems [PDF]

open access: yesMathematica Bohemica, 2006
Summary: Observability of a general nonlinear system -- given in terms of an ODE \(\dot {x}=f(x)\) and an output map \(y=c(x)\) -- is defined as in linear system theory (i.e.\,if \(f(x)=Ax\) and \(c(x)=Cx\)). In contrast to standard treatment of the subject we present a criterion for observability which is not a generalization of a known linear test ...
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Tricomi Problem for a Second-Kind Mixed-Type Equation in a Domain Whose Elliptic Part Is a Vertical Half-Strip

open access: yesMathematics
In this paper, the Tricomi problem for a second-kind mixed-type equation with a lower-order term is studied in an unbounded domain. The elliptic part of the domain is a vertical half-strip, while the hyperbolic part is bounded by characteristics ...
Rakhimjon Zunnunov   +2 more
doaj   +1 more source

Pattern-Moving-Based Partial Form Dynamic Linearization Model Free Adaptive Control for a Class of Nonlinear Systems

open access: yesActuators, 2021
This work addresses a pattern-moving-based partial form dynamic linearization model free adaptive control (P-PFDL-MFAC) scheme and illustrates the bounded convergence of its tracking error for a class of unknown nonaffine nonlinear discrete-time systems.
Xiangquan Li, Zhengguang Xu
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The passivity of adaptive output regulation of nonlinear exosystem with application of aircraft motions [PDF]

open access: yes, 2017
This paper deals with passivity of adaptive output regulation of nonlinear exosystem. It is shown that factorisable low-high frequency gains and harmonic uncertainties are estimated to the exogenous signals with adaptive nonlinear system.
Kumar, R. Ravi Ravi   +2 more
core   +1 more source

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