Results 31 to 40 of about 395,573 (268)

Systems of nonlinear wave equations with nonlinear viscosity [PDF]

open access: yesPacific Journal of Mathematics, 1988
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Friedman, Avner, Nečas, Jindřich
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Symmetries, stability, and control in nonlinear systems and networks

open access: yes, 2011
This paper discusses the interplay of symmetries and stability in the analysis and control of nonlinear dynamical systems and networks. Specifically, it combines standard results on symmetries and equivariance with recent convergence analysis tools based
RUSSO G   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Factorization of Nonlinear Systems [PDF]

open access: yes, 1989
Summary: A basic result of \textit{H. Bart}, \textit{I. Gohberg} and \textit{M. A. Kaashoek} [Minimal factorization of matrix and operator functions (1979; Zbl 0424.47001)] parametrizes factorizations of the transfer function of a linear system in terms of the state space equations of the system. This paper extends their result to nonlinear systems.
openaire   +2 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Perturbation solutions of fifth order oscillatory nonlinear systems

open access: yes, 2011
Oscillatory systems play an important role in the nature. Many engineering problems and physical systems of fifth degrees of freedom are oscillatory and their governing equations are fifth order nonlinear differential equations.
Akbar, M. Ali Ali   +1 more
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Nonlinear Systems

open access: yes
Open Mathematics is a challenging notion for theoretical modeling, technical analysis, and numerical simulation in the fields of physics and mathematics, among others, as highly correlated nonlinear phenomena, evolving over a large range of time and ...

core   +1 more source

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