Results 31 to 40 of about 395,573 (268)
Systems of nonlinear wave equations with nonlinear viscosity [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Friedman, Avner, Nečas, Jindřich
openaire +2 more sources
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Symmetries, stability, and control in nonlinear systems and networks
This paper discusses the interplay of symmetries and stability in the analysis and control of nonlinear dynamical systems and networks. Specifically, it combines standard results on symmetries and equivariance with recent convergence analysis tools based
RUSSO G +5 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Factorization of Nonlinear Systems [PDF]
Summary: A basic result of \textit{H. Bart}, \textit{I. Gohberg} and \textit{M. A. Kaashoek} [Minimal factorization of matrix and operator functions (1979; Zbl 0424.47001)] parametrizes factorizations of the transfer function of a linear system in terms of the state space equations of the system. This paper extends their result to nonlinear systems.
openaire +2 more sources
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Perturbation solutions of fifth order oscillatory nonlinear systems
Oscillatory systems play an important role in the nature. Many engineering problems and physical systems of fifth degrees of freedom are oscillatory and their governing equations are fifth order nonlinear differential equations.
Akbar, M. Ali Ali +1 more
core +1 more source
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie +3 more
wiley +1 more source
Open Mathematics is a challenging notion for theoretical modeling, technical analysis, and numerical simulation in the fields of physics and mathematics, among others, as highly correlated nonlinear phenomena, evolving over a large range of time and ...
core +1 more source

