Results 41 to 50 of about 443,808 (279)

Attractor reconstruction of an impact oscillator for parameter identification [PDF]

, 2015
Peer ...
Baptista, Murilo Da Silva, Ing, James, Sayah, Mukthar, Wiercigroch, Marian   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Nonlinear Variable Parameter Time History Analysis on Dynamic Response of Timber Frame in Song Dynasty Palace

Taiyuan Ligong Daxue xuebao, 2021
In order to study the dynamic response of timber frame in Song Dynasty palace under horizontal acceleration, a series of nonlinear time-history analysis FE models were estallihed.
Jia WAN, Renfu GUO, Xiaochen MI, Jianwei WEI, Tieying LI   +4 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Comparison of the IDA and ET on Steel Structures Rehabilitated by Isolators [PDF]

Journal of Rehabilitation in Civil Engineering, 2014
Endurance time (ET) method is a relatively new performance-based earthquake method for structural evaluation and design. In this method, the structure is subjected to a gradually intensifying accelorogram(s) and its performance is assessed based on the ...
Hamed Arshadi, Ramezan Ali Izadifard, Homayun Estekanchi   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Evaluation of Advanced Nonlinear Static Procedure [PDF]

Journal of Structural and Construction Engineering, 2015
Having very simplicity, nonlinear static procedures (NSPs) are the most popular tools for estimation of structural capacity. These approaches construct a graphic display of the overall structural response via a pushover curve. The overall response of the
Mohsen Ali Shayanfar, Reza ZareBidoki
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Analysis of Retrofit Building Behavior with Base Isolation System Using Nonlinear Time History Analysis

IPTEK Journal of Proceedings Series, 2017
Now,  procedures of design for the earthquake resistance of buildings and non-building structures SNI 1726: 2012 has been approved the procedures for seismic design for buildings SNI 1726-2002.  SNI 1726: 2012 refers to the development  of  modern seismic regulations are due to changes in tectonic plates located on the active track on the path of ...
Yanisfa Septiarsilia, Tavio Tavio, I Gusti Putu Raka   +2 more
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source