Results 61 to 70 of about 447,237 (298)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Analisis Perilaku Struktur Beton dan Baja Dengan Metode Levelling Time History (Studi Kasus Gedung ITERA, Lampung, Indonesia)

Rekayasa Sipil, 2019
The selection of structural material types can be based on analyzing the behavioral of the structure by giving a nonlinear dynamic earthquake load of time history.
Ahmad Yudi, Bayzoni, Nugraha Bintang Wirawan, Rijuli Nadeak   +3 more
doaj   +1 more source

A case study on an innovative seismic performance evaluation procedure for irregular RC buildings

Frontiers in Built Environment, 2022
Assessing the structural capacity of an irregular structure requires an appropriate and robust representation of the analytical model. Conventional procedures are flawed because they lack the reversal effects of higher modes.
Resat A. Oyguc
doaj   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Real-Time City-Scale Time-History Analysis and Its Application in Resilience-Oriented Earthquake Emergency Responses

Applied Sciences, 2019
The resilience of cities has received worldwide attention. An accurate and rapid assessment of seismic damage, economic loss, and post-event repair time can provide an important reference for emergency rescue and post-earthquake recovery.
Xinzheng Lu, Qingle Cheng, Zhen Xu, Yongjia Xu, Chujin Sun   +4 more
doaj   +1 more source

Modelling strong seismic ground motion: three-dimensional loading path versus wavefield polarization [PDF]

, 2012
Seismic waves due to strong earthquakes propagating in surficial soil layers may both reduce soil stiffness and increase the energy dissipation into the soil.
D'Avila, Maria Paola Santisi, Lenti, Luca, Semblat, Jean-François   +2 more
core   +6 more sources

An Efficient Computational Strategy for Nonlinear Time History Analysis of Seismically Base-Isolated Structures

, 2020
Nonlinear time history analysis represents the most appropriate structural analysis procedure to accurately analyze seismically base-isolated structures since their dynamic response is typically governed by a system of coupled nonlinear ordinary differential equations of the second order in time.
Vaiana N., Sessa S., Paradiso M., Marmo F., Rosati L.   +4 more
openaire   +2 more sources

Development of seismic fragility surfaces for reinforced concrete buildings by means of nonlinear time‐history analysis [PDF]

Earthquake Engineering & Structural Dynamics, 2009
AbstractFragility curves are generally developed using a single parameter to relate the level of shaking to the expected structural damage. The main goal of this work is to use several parameters to characterize the earthquake ground motion. The fragility curves will, therefore, become surfaces when the ground motion is represented by two parameters ...
Seyedi, Darius, Gehl, Pierre, Douglas, John, Davenne, L., Mezher, N., Ghavamian, S.   +5 more
openaire   +2 more sources

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

The Effect of Spandrel Beam's Specification on Response Modification Factor of Concrete Coupled Shear Walls [PDF]

Civil Engineering Infrastructures Journal, 2016
Response modification factor (R factor) is one of the seismic design parameters to be considered in evaluating the performance of buildings during strong motions. This paper has tried to evaluate the response modification factor of concrete coupled shear
Mussa Mahmoudi, seyed Mohammad Reza Mortazavi, Saeid Ajdari   +2 more
doaj   +1 more source