Results 41 to 50 of about 84,115 (259)

Nonlinear Variable Parameter Time History Analysis on Dynamic Response of Timber Frame in Song Dynasty Palace

open access: yesTaiyuan Ligong Daxue xuebao, 2021
In order to study the dynamic response of timber frame in Song Dynasty palace under horizontal acceleration, a series of nonlinear time-history analysis FE models were estallihed.
Jia WAN   +4 more
doaj   +1 more source

Nonlinear Time-History Analysis of Soil-Structure Systems Incorporating Frequency-Dependent Impedance Functions

open access: yesCoRR, 2023
To accurately analyze structures, soil-structure interaction effects must be taken into account. One approach is to create a complete finite element model of the full system wherein the soil is represented as a semi-infinite domain. This direct method is frequently adopted in research studies, but it is typically avoided in engineering practice due to ...
S. Farid Ghahari   +3 more
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Effect of U-Shaped Metallic Dampers on the Seismic Performance of Steel Structures based on Endurance-Time Analysis

open access: yesBuildings
Seismic performance of steel moment-resisting frames is investigated through the incorporation of U-shaped metallic dampers. The primary objective is to assess the effectiveness of these dampers in mitigating seismic responses by utilizing various ...
Farhad Farajiani   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Enhanced Earthquake Performance of Existing RC Buildings Through Hybrid CFRP and Damper Retrofitting

open access: yesBuildings
Interest in applying hybrid retrofitting approaches to existing buildings is steadily increasing. In this study, an attempt was made to seismically retrofit an RC (reinforced concrete) building using CFRP (carbon fiber-reinforced polymer) and dampers ...
Hakan Koman, Abdullah Niğdelioğlu
doaj   +1 more source

Analisis Perilaku Struktur Beton dan Baja Dengan Metode Levelling Time History (Studi Kasus Gedung ITERA, Lampung, Indonesia)

open access: yesRekayasa Sipil, 2019
The selection of structural material types can be based on analyzing the behavioral of the structure by giving a nonlinear dynamic earthquake load of time history.
Ahmad Yudi   +3 more
doaj   +1 more source

Rapid Seismic Evaluation of Continuous Girder Bridges with Localized Plastic Hinges

open access: yesSensors, 2022
In seismic assessment of continuous girder bridges, plastic hinges form in bridge piers to dissipate seismic energy through nonlinear restoring forces.
Zhaolan Wei   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy