Results 71 to 80 of about 443,808 (279)

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

The Assessment and Comparison of Tall Buildings with Outrigger and Belt Truss Systems Using Fragility Curves [PDF]

Journal of Structural and Construction Engineering, 2018
In the design of high-rise buildings, three parameters such as resistance, hardness and stability are very important and when the height of building rises, effect of toughness and stability in optimum design will be dominate more than of the effects of ...
Hamed Hamidi, Jafar Pakdaman, Ehsan Jahani, Hamid Rajabnejad   +3 more
doaj   +1 more source

Motor deficits in schizophrenia quantified by nonlinear analysis of postural sway. [PDF]

, 2012
Motor dysfunction is a consistently reported but understudied aspect of schizophrenia. Postural sway area was examined in individuals with schizophrenia under four conditions with different amounts of visual and proprioceptive feedback: eyes open or ...
Bolbecker, Amanda R., Forsyth, Jennifer K., Hetrick, William P., Hong, S. Lee, Kent, Jerillyn S., Klaunig, Mallory J., O'Donnell, Brian F.   +6 more
core   +3 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Seismic Upgrade of an Existing Reinforced Concrete Building Using Steel Plate Shear Walls (SPSW)

Applied Sciences
Steel Plate Shear Walls (SPSW) provide significant lateral load capacity and can be utilized in the seismic retrofit and upgrade of existing reinforced concrete (r/c) buildings.
Niki Balkamou, George Papagiannopoulos
doaj   +1 more source

Speeding Up Nonlinear Time History Analysis Of Base-Isolated Structures Using A Nonlinear Exponential Model

, 2017
The nonlinear time history analysis of seismically base-isolated structures can require a significant computational effort when the behavior of each seismic isolator is predicted by adopting the widely used differential equation Bouc-Wen model. In this paper, a nonlinear exponential model, able to simulate the response of seismic isolation bearings ...
Vaiana, Nicolò, Serino, Giorgio
openaire   +1 more source

Evaluation of a wave-vector-frequency-domain method for nonlinear wave propagation [PDF]

, 2011
A wave-vector-frequency-domain method is presented to describe one-directional forward or backward acoustic wave propagation in a nonlinear homogeneous medium.
Duck F. A., Greg T. Clement, Kuznetsov V, Molei Tao, Yun Jing   +4 more
core   +2 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Properties and stability of freely propagating nonlinear density waves in accretion disks [PDF]

, 2007
In this paper, we study the propagation and stability of nonlinear sound waves in accretion disks. Using the shearing box approximation, we derive the form of these waves using a semi-analytic approach and go on to study their stability.
Arras, Artymowicz, Balbus, Balbus, Bate, Fromang, Goldreich, Goldreich, Goldreich, Goodman, Hawley, J. Papaloizou, Kato, Kerswell, Korycansky, Larson, Lin, Lin, Lin, Lubow, Lubow, Lynden-Bell, Nelson, Ogilvie, Ogilvie, Papaloizou, Papaloizou, Papaloizou, S. Fromang, Teyssier, Torkelsson, Ziegler   +31 more
core   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source