Results 41 to 50 of about 19,312,029 (301)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Photoplethysmogram Recording Length: Defining Minimal Length Requirement from Dynamical Characteristics

open access: yesSensors, 2022
Photoplethysmography is a widely used technique to noninvasively assess heart rate, blood pressure, and oxygen saturation. This technique has considerable potential for further applications—for example, in the field of physiological and mental health ...
Nina Sviridova   +3 more
doaj   +1 more source

Nonlinear Time Series 2013 [PDF]

open access: yesMathematical Problems in Engineering, 2014
n ...
Ming, Li   +3 more
openaire   +4 more sources

Nonlinear Error Correction Models [PDF]

open access: yes, 2002
The relationship between cointegration and error correction (EC) models is well characterized in a linear context, but the extension to the nonlinear context is still a challenge.
Escribano, Álvaro, Mira, Santiago
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Forecasting high waters at Venice Lagoon using chaotic time series analisys and nonlinear neural netwoks [PDF]

open access: yes, 2000
Time series analysis using nonlinear dynamics systems theory and multilayer neural networks models have been applied to the time sequence of water level data recorded every hour at 'Punta della Salute' from Venice Lagoon during the years 1980-1994.
Zaldívar, J.M.   +4 more
core   +1 more source

Nonlinear Time Series Analysis and Prediction of General Aviation Accidents Based on Multi-Timescales

open access: yesAerospace, 2023
General aviation accidents have complex interactions and influences within them that cannot be simply explained and predicted by linear models. This study is based on chaos theory and uses general aviation accident data to conduct research on different ...
Yufei Wang   +4 more
doaj   +1 more source

Linear and nonlinear filtering in mathematical finance: a review [PDF]

open access: yes, 2010
Copyright @ The Authors 2010This paper presents a review of time series filtering and its applications in mathematical finance. A summary of results of recent empirical studies with market data are presented for yield curve modelling and stochastic ...
Date, P   +3 more
core   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu   +7 more
wiley   +1 more source

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