Results 31 to 40 of about 71,375 (269)
Frontiers in EndocrinologyObjectiveCurrent research on the association between the Gamma-glutamyl transferase to high-density lipoprotein ratio (GHR) and the risk of prediabetes (pre-DM) remains scarce.
Chuang Gao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
L1 Adaptive Control for a Vertical Rotor Orientation System
Applied Sciences, 2016 Bottom-fixed vertical rotating devices are widely used in industrial and civilian fields. The free upside of the rotor will cause vibration and lead to noise and damage during operation.
Sijia Liu, Yu Fan, Jun Di, Mingming Ji
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2001 The simultaneous propagation of two optical pulses through a doped nonlinear dispersive medium modelled by a resonant three-level system was investigated numerically, within the framework of a pair of coupled extended nonlinear Schrödinger equations ...
SOLANGE B. CAVALCANTI +3 more
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Nonlinear Pulse-Time Conversion in Radioisotope Devices: Analysis and Application Possibilities
Приборы и методы измерений, 2021 The paper considers the operation of radioisotope measuring devices under dynamic conditions, when the Poisson pulse flux at the output of the radiation detector becomes unsteady and the nonlinearity of the calibration curve of the device, the ...
A. M. Vodovozov
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Dose-response meta-analysis: application and practice using the R software [PDF]
Epidemiology and Health, 2019 The objective of this study was to describe the general approaches of dose-response meta-analysis (DRMA) available for the quantitative synthesis of data using the R software.
Sung Ryul Shim, Jonghoo Lee
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Frequency response areas in the inferior colliculus: nonlinearity and binaural interaction
Frontiers in Neural Circuits, 2013 The tuning, binaural properties, and encoding characteristics of neurons in the central nucleus of the inferior colliculus (CNIC) were investigated to shed light on nonlinearities in the responses of these neurons.
Jane J Yu, Eric Daniel Young
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