Results 51 to 60 of about 407,249 (301)

Giant nonlinearity via breaking parity-time symmetry: a route to low-threshold phonon diodes

open access: yes, 2015
Nonreciprocal devices that permit wave transmission in only one direction are indispensible in many fields of science including, e.g., electronics, optics, acoustics, and thermodynamics.
Jing, Hui   +8 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Nonlinear association between gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio and risk of progression from normoglycemia to prediabetes: a 5-year cohort study

open access: yesFrontiers in Endocrinology
ObjectiveCurrent research on the association between the Gamma-glutamyl transferase to high-density lipoprotein ratio (GHR) and the risk of prediabetes (pre-DM) remains scarce.
Chuang Gao   +5 more
doaj   +1 more source

Nonlinear Schrodinger equations with repulsive harmonic potential and applications

open access: yes, 2003
We study the Cauchy problem for Schrodinger equations with repulsive quadratic potential and power-like nonlinearity. The local problem is well-posed in the same space as that used when a confining harmonic potential is involved.
Dunford Nelson, Kato Tosio, Rémi Carles
core   +3 more sources

Effect of nonlinearity on the dynamics of a particle in dc field-induced systems [PDF]

open access: yes, 1998
Dynamics of a particle in a perfect chain with one nonlinear impurity and in a perfect nonlinear chain under the action of dc field is studied numerically. The nonlinearity appears due to the coupling of the electronic motion to optical oscillators which
A. M. Jayannavar   +13 more
core   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

L1 Adaptive Control for a Vertical Rotor Orientation System

open access: yesApplied Sciences, 2016
Bottom-fixed vertical rotating devices are widely used in industrial and civilian fields. The free upside of the rotor will cause vibration and lead to noise and damage during operation.
Sijia Liu, Yu Fan, Jun Di, Mingming Ji
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Coherent soliton propagation through doped optical fibers: cloning, breakup, and soliton interactions

open access: yesAnais da Academia Brasileira de Ciências, 2001
The simultaneous propagation of two optical pulses through a doped nonlinear dispersive medium modelled by a resonant three-level system was investigated numerically, within the framework of a pair of coupled extended nonlinear Schrödinger equations ...
SOLANGE B. CAVALCANTI   +3 more
doaj   +1 more source

Nonlinear Pulse-Time Conversion in Radioisotope Devices: Analysis and Application Possibilities

open access: yesПриборы и методы измерений, 2021
The paper considers the operation of radioisotope measuring devices under dynamic conditions, when the Poisson pulse flux at the output of the radiation detector becomes unsteady and the nonlinearity of the calibration curve of the device, the ...
A. M. Vodovozov
doaj   +1 more source

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