Results 51 to 60 of about 70,037 (214)

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Skin Cancer Predisposition Genes, Full‐Body Skin Examinations, Familial Disclosure, and Genetic Testing Among High‐Risk Individuals

International Journal of Dermatology, EarlyView.
ABSTRACT Background There is a lack of knowledge in full‐body skin examinations (FBSEs) in the context of pathogenic or likely pathogenic variants (PV/LPV) in skin cancer predisposition genes (CPGs). This study assessed the association between carrier status of PV/LPV in skin CPGs and FBSEs and described the patterns of family letter receipt, familial ...
Jincong Q. Freeman, Yu Matsui, Fangyuan Zhao, Olufunmilayo I. Olopade, Dezheng Huo   +4 more
wiley   +1 more source

Development and validation of a deep learning model for improving detection of nonmelanoma skin cancers treated with Mohs micrographic surgeryCapsule Summary

JAAD International
Background: Real-time review of frozen sections underpins the quality of Mohs surgery. There is an unmet need for low-cost techniques that can improve Mohs surgery by reliably corroborating cancerous regions of interest and surgical margin proximity ...
Eugene Tan, MBChB, Sophie Lim, MBBS, Duncan Lamont, MMed, Richard Epstein, MBBS, PhD, David Lim, MBChB, Frank P.Y. Lin, MBChB, PhD   +5 more
doaj   +1 more source

Teledermatology: From Prevention to Diagnosis of Nonmelanoma and Melanoma Skin Cancer

International Journal of Telemedicine and Applications, 2011
Telemedicine is a rapidly developing application of clinical medicine where medical information is transferred through interactive audiovisual media for the purpose of consulting remote medical procedures or examinations, reducing the time of ...
G. Fabbrocini, V. De Vita, F. Pastore, V. D'Arco, C. Mazzella, M. C. Annunziata, S. Cacciapuoti, M. C. Mauriello, A. Monfrecola   +8 more
doaj   +1 more source

Risk of a Second Primary Cancer after Non-melanoma Skin Cancer in White Men and Women: A Prospective Cohort Study [PDF]

, 2013
Background: Previous studies suggest a positive association between history of non-melanoma skin cancer (NMSC) and risk of subsequent cancer at other sites.
Chen, Wendy Yvonne, Fuchs, Charles Stewart, Giovannucci, Edward L., Han, Jiali, Qureshi, Abrar A., Song, Fengju, Stampfer, Meir Jonathan   +6 more
core   +3 more sources

Assessing the Dermal Epidermal Junction of Hyperkeratotic Actinic Keratoses via Line‐Field Confocal Optical Coherence Tomography

International Journal of Dermatology, EarlyView.
Actinic keratoses (AK) are ultraviolet (UV)‐correlated precursor lesions of invasive cutaneous squamous cell carcinoma (iSCC). AK thickness does not correlate with increased iSCC transformation, but dermal‐epidermal junction (DEJ) protrusion does. The DEJ of hyperkeratotic lesions is harder to study via line‐field confocal optical coherence tomography (
Simone Michelini, Pietro Scribani Rossi, Giuseppe Gemma, Flavia Persechino, Giordano Vespasiani, Claudio Conforti, Francesco Ricci, Carmen Cantisani, Giovanni Pellacani   +8 more
wiley   +1 more source

Keratinocyte Carcinomas:Current concepts and future research priorities [PDF]

, 2018
Cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC) are keratinocyte carcinomas (KC), the most frequently diagnosed cancers in fair-skinned populations.
Arron, Sarah T., Asgari, Maryam M., Ewart Toland, Amanda, Green, Adele C., Guhan, Samantha M., Harwood, Catherine A., Nagarajan, Priyadharsini, Proby, Charlotte, Rollison, Dana E.   +8 more
core   +2 more sources

Acral Melanocytic Lesions Under Conventional, Sub‐Ultraviolet Reflectance, and Ultraviolet‐Induced Fluorescence Dermoscopy: A Comparative Analysis

International Journal of Dermatology, EarlyView.
Conventional dermoscopy provided higher scores than ultraviolet‐induced fluorescence dermoscopy for parallel furrow pattern, parallel ridge pattern (PRP), fibrillar pattern, dots/clods, radial lines, blue–white structureless areas and blotch, and outperformed sub‐ultraviolet reflectance dermoscopy (sUVRD) for PRP and blue–white structureless areas ...
Handan Merve Erol Mart, Ahmet Taha Aydemir, Pawel Pietkiewicz, Bengu Nisa Akay   +3 more
wiley   +1 more source

Friend or foe? The current epidemiologic evidence on selenium and human cancer risk. [PDF]

, 2013
Scientific opinion on the relationship between selenium and the risk of cancer has undergone radical change over the years, with selenium first viewed as a possible carcinogen in the 1940s then as a possible cancer preventive agent in the 1960s-2000s ...
Ammar E M, Bhattacharya A, Bjelakovic G, Blot W J, Buntzel J, CARLOTTA MALAGOLI, CATHERINE M. CRESPI, CINZIA DEL GIOVANE, Clayton C C, Cortes-Jofre M, Csallany A S, Dalkin B W, Dennert G, Dreno B, Duffield-Lillico A J, Hafeman D G, Hartman T J, Hercberg S, Hunter D J, Karp D D, Kim Y W, Kok F J, Krogh V, Levander OA., Li H, Li W, Lillico A, MARCO VINCETI, Marshall J R, Nelson A A, Ovaskainen M L, Peleg I, Ravn-Haren G, Rees K, Reid M E, Rothman K J, Salbe A D, Salbe A D, Salonen J T, Shamberger R J, Sunde RA., Swanson C A, Trougakos IP., van den Brandt P A, Vinceti M, Vinceti M, VITTORIO KROGH, Zheng S, Zhuo H   +48 more
core   +1 more source

International Dermoscopy Society consensus recommendations for the management of lentigo maligna

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Lentigo maligna (LM) poses diagnostic and therapeutic challenges amid rising incidence and limited high‐quality evidence. This international expert consensus provides pragmatic, evidence‐based and expertise‐informed guidance on LM diagnosis and management.
Ana‐Maria Forsea, Riccardo Pampena, Bengu Nisa Akay, Zoe Apalla, Giuseppe Argenziano, Giulia Briatico, Ralph Braun, Horacio Cabo, Raul Cabrera, Cristina Carrera, Elisa Cinotti, Claudio Conforti, Enzo Errichetti, Gerardo Ferrara, Roberta Giuffrida, Stefania Guida, Pascale Guitera, Allan C. Halpern, Stephen Heyes, Rainer Hofmann‐Wellenhof, Angela M. Hong, Natalia Jaimes, Raimonds Karls, Harald Kittler, Teresa Kränke, Konstantinos Liopyris, Jie Liu, Caterina Longo, Josep Malvehy, Ashfaq A. Marghoob, Hoda Moneib, David Moreno Ramirez, Elvira Moscarella, Eduardo Nagore, Cristian Navarrete‐Dechent, John Paoli, Giovanni Pellacani, Ketty Peris, Susana Puig, Cliff Rosendahl, Lidia Rudnicka, Ahmed Sadek, Philippe Saiag, Gabriel Salerni, Alon Scope, Hans Peter Soyer, Michela V. Starace, Wilhelm Stolz, David L. Swanson, Luc Thomas, Philipp Tschandl, Iris Zalaudek, Aimilios Lallas   +52 more
wiley   +1 more source