Results 71 to 80 of about 3,795,575 (208)

One cycle of nelarabine given after induction is well tolerated but does not improve outcome in adults with T‐cell precursor acute lymphoblastic leukemia: Outcome data from the UKALL14 randomized‐controlled trial

HemaSphere, Volume 10, Issue 10, October 2026.
Abstract UKALL14 (NCT01085617) T‐cell arm was a phase 3, randomized‐controlled trial. Adults aged 25–65 years were randomized 1:1 at entry to receive standard of care (SOC) or SOC + nelarabine 1.5 g/m2 (Days 1, 3, and 5) to be administered following second induction. The primary end‐point was event‐free survival (EFS).
Clare J. Rowntree, Amy A. Kirkwood, Nadine Farah, Emma Lawrie, David I. Marks, Andrew K. McMillan, Tobias F. Menne, Anthony V. Moorman, Bela Patel, Pip Patrick, Paul Smith, Krisztina Z. Alapi, Lingyi Wang, Marc R. Mansour, Adele K. Fielding   +14 more
wiley   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source

Optimising Melanoma Diagnostic Accuracy in Specialised Pigmented Lesion Clinics: A Five‐Year Audit of Number Needed to Treat

Australasian Journal of Dermatology, EarlyView.
C. Ramirez, M. A. El Sharouni, L. Clavero‐Rovira, B. Gallo, B. Gouveia, C. Sinz, S. Kapila, A. Glanz, H. Collgros, A. E. Cust, L. K. Martin, P. Guitera   +11 more
wiley   +1 more source

A Deep‐Learning Based Biomarker of Systemic Cellular Senescence Burden to Predict Mortality and Health Outcomes

Aging Cell, Volume 25, Issue 10, October 2026.
Using 38 blood SASP proteins, a guided autoencoder‐transformer model generates a composite SASP Score that captures systemic cellular senescence burden. The score predicts mortality and age‐related diseases, outperforms individual proteins, and supports cross‐platform biomarker translation.
Shangshu Zhao, Chia‐Ling Kuo, Eric J. Lenze, Julie L. Wetherell, Laura Haynes, Perla El‐Ahmad, Richard Fortinsky, George Kuchel, Trevor Harris, Breno S. Diniz   +9 more
wiley   +1 more source

Cancer trends no 20. non-melanoma skin cancer [PDF]

, 2013
Between 1994 and 2011, an average of 6,899 cases of invasive skin cancer was diagnosed per year in Ireland. Malignant melanoma accounted for just over 8% of this number; the vast bulk of all invasive skin cancers being non-melanomatous subtypes, of ...
National Cancer Registry Ireland (NCRI)
core  

Protein Profile of Multiple Myeloma‐Derived Extracellular Vesicles for the Discovery of Novel Myeloma‐Related Biomarkers

Cancer Science, Volume 117, Issue 10, Page 2877-2890, October 2026.
Comparison of extracellular vesicles with parental cells through proteomic profiling, followed by an integrated bioinformatic pipeline including disease association and transcriptomic analyses, identifies candidate biomarkers for multiple myeloma. Among these, MIF emerges as a clinically relevant marker, supported by validation in patient samples and ...
Natalia Platonova, Gilda Aiello, Domenica Ronchetti, Valentina Citro, Rosanna Asselta, Lavinia Casati, Domenica Giannandrea, Elisa Taiana, Antonino Neri, Gloria Sini, Elisabetta Calzavara, Mauro Turrini, Alfonsina D'Amato, Raffaella Chiaramonte   +13 more
wiley   +1 more source

International Dermoscopy Society consensus recommendations for the management of lentigo maligna

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page 1600-1617, October 2026.
Lentigo maligna (LM) poses diagnostic and therapeutic challenges amid rising incidence and limited high‐quality evidence. This international expert consensus provides pragmatic, evidence‐based and expertise‐informed guidance on LM diagnosis and management.
Ana‐Maria Forsea, Riccardo Pampena, Bengu Nisa Akay, Zoe Apalla, Giuseppe Argenziano, Giulia Briatico, Ralph Braun, Horacio Cabo, Raul Cabrera, Cristina Carrera, Elisa Cinotti, Claudio Conforti, Enzo Errichetti, Gerardo Ferrara, Roberta Giuffrida, Stefania Guida, Pascale Guitera, Allan C. Halpern, Stephen Heyes, Rainer Hofmann‐Wellenhof, Angela M. Hong, Natalia Jaimes, Raimonds Karls, Harald Kittler, Teresa Kränke, Konstantinos Liopyris, Jie Liu, Caterina Longo, Josep Malvehy, Ashfaq A. Marghoob, Hoda Moneib, David Moreno Ramirez, Elvira Moscarella, Eduardo Nagore, Cristian Navarrete‐Dechent, John Paoli, Giovanni Pellacani, Ketty Peris, Susana Puig, Cliff Rosendahl, Lidia Rudnicka, Ahmed Sadek, Philippe Saiag, Gabriel Salerni, Alon Scope, Hans Peter Soyer, Michela V. Starace, Wilhelm Stolz, David L. Swanson, Luc Thomas, Philipp Tschandl, Iris Zalaudek, Aimilios Lallas   +52 more
wiley   +1 more source

Genetics and nonmelanoma skin cancer in kidney transplant recipients

, 2015
Summary Pharmacogenomics Vol. 16, No. 2, Pages 161-172 , DOI 10.2217/pgs.14.156 (doi:10.2217/pgs.14.156) Review Genetics and nonmelanoma skin cancer in kidney transplant recipients Michael T Burke*,1, Nicole Isbel1, Katherine A Barraclough2, Ji-Won Jung3,
Barraclough, Katherine A., Jung, Ji-Won, Wells, James W., Staatz, Christine E., Isbel, Nicole, Burke, Michael T.   +5 more
core   +1 more source

Increased expression of CD24 in nonmelanoma skin cancer

The International Journal of Biological Markers, 2012
Background Skin cancer detection is based on the macroscopic and microscopic appearance of the lesions and the experience of the surgeon. The final diagnosis is done by pathological analysis, based on established criteria.
Ehud Miller, Shiran Shapira, Eyal Gur, Inna Naumov, Dina Kazanov, David Leshem, Yoav Barnea, Yaakov Meshiach, Andrea Gat, Daniel Sion, Nadir Arber MD, MSc, MHA, Sarah Kraus   +11 more
doaj   +1 more source

Elevated risk of ischemic stroke after invasive cancer diagnosis: A nationwide population‐based study

Cancer, Volume 132, Issue 18, 15 September 2026.
Abstract Background Cancer and stroke are major causes of morbidity and mortality, with an increasing shared burden. This study aimed to provide population‐based estimates of ischemic stroke (IS) risk after cancer diagnosis across multiple cancer sites and demographic subgroups.
Carmit Libruder, David Tanne, Barbara G. Silverman, Binyamin Binyaminy, Rita Dichtiar, Lital Keinan‐Boker   +5 more
wiley   +1 more source