Results 71 to 80 of about 70,037 (214)

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

Photochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye, Debra R. Garvey, Gagan Chhabra, Chandra K. Singh, Minakshi Nihal, Nihal Ahmad   +5 more
wiley   +1 more source

Cost-effectiveness of surgical excision versus Mohs micrographic surgery for nonmelanoma skin cancer: A retrospective cohort study

Journal of Research in Medical Sciences, 2016
Background: Nonmelanoma skin cancer rates are increasing worldwide. Mohs micrographic surgery and surgical excision (SE) are the two treatment methods for this type of cancer.
Leila Nassiripour, Mohammadreza Amirsadri, Maryam Tabatabaeian, Mohammad Reza Maracy   +3 more
doaj   +1 more source

Dermatological Malignancies at a University Teaching Hospital in north-western Tanzania: A Retrospective Review of 154 Cases [PDF]

, 2012
Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution ...
Chalya, Phillipo L., Gilyoma, Japhet M., Kahima, Kahima J., Kanumba, Emmanuel S., Masalu, Nestory, Mawala, Brian, Rambau, Peter   +6 more
core   +2 more sources

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Peculiar features of non-melanoma skin cancers in organ transplant patients [PDF]

, 2016
Le neoplasie cutanee non melanoma (NMSCs) hanno un’aumentata incidenza tra i pazienti trapiantati d’organo. L’obiettivo di questo studio è quello di comparare gli aspetti clinico-patologici dei NMSCs dei pazienti trapiantati con quelli dei soggetti ...
Infusino, Salvatore Domenico <1980>
core   +1 more source

Clinical benefit and predictors of response to momelotinib after ruxolitinib failure: A cooperative real‐world study

Cancer, Volume 132, Issue 10, 15 May 2026.
Momelotinib demonstrated robust real‐world activity after ruxolitinib failure, with clinically meaningful improvements in spleen (≥50% spleen length reduction, 30.0%), symptoms (≥50% total symptoms score reduction, 39.2%), and anemia (major response, 35.7%) at 6 months.
Francesca Palandri, Monia Marchetti, Elena M. Elli, Alessandro Isidori, Ilaria Gianesello, Chiara Sartor, Novella Pugliese, Maria Di Perna, Erika Morsia, Susanna Gallo, Federico Itri, Vittorio Montefusco, Elena Crisà, Annalisa Biagi, Eloise Beggiato, Olga Mulas, Giulia Benevolo, Elisabetta Abruzzese, Marco Santoro, Alessandra Iurlo, Elisabetta Calistri, Marco Rossi, Bruno Martino, Mario Tiribelli, Carmen Fava, Arbana Dizdari, Monica Crugnola, Andrea Duminuco, Amedeo Votto, Selene Guerzoni, Giovanni Caocci, Fabrizio Pane, Francesco Lanza, Filippo Branzanti, Alessandra Dedola, Flavia Salvatore, Florian H. Heidel, Massimo Breccia, Giuseppe A. Palumbo, Andrew T. Kuykendall, Alessandro Lucchesi, Sara Galimberti   +41 more
wiley   +1 more source

Cutis verticis gyrata in a patient with multiple basal cell carcinomas; case presentation and review of the literature [PDF]

, 2016
Cutis verticis gyrata is a rare disease characterized by convoluted folds and deep furrows of the scalp, resembling the gyri and sulci of the cerebral cortex.
Benea, Vasile, Georgescu, Simona Roxana, Mitran, Cristina Iulia, Mitran, Mădălina Irina, Rusu, Alice, Sârbu, Maria Isabela, Tampa, Mircea   +6 more
core   +4 more sources

Exploring What Constitutes a Good‐Quality Referral for a Potentially Malignant Skin Lesion: A Modified Delphi Consensus

International Journal of Dermatology, EarlyView.
Kristina Nazzicone, Erin Dahlke, Linden Head, Thomas Herzinger, Lourdes Ramírez Hobak, Yuanshen Huang, Menelaos Konstantinidis, Glykeria Martou, Sonja Molin, Douglas R. McKay, Yuka Asai   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, Volume 20, Issue 5, Page 1323-1346, May 2026.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Skin Cancer: Causes, Prevention, and Treatment [PDF]

, 2017
The purpose of this thesis is to analyze the causes, prevention, and treatment of skin cancer. Skin cancers are defined as either malignant or benign cells that typically arise from excessive exposure to UV radiation.
Queen, Lauren
core