Results 171 to 180 of about 1,436,982 (204)
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2017
With the emergence of quality of life measures as an indicator for the impact of medical and surgical interventions in dystonia, focus has shifted toward unraveling the pathophysiology and neuroanatomical basis of the "nonmotor symptoms" (NMS). To date, the NMS are now recognized as the greater determinant of quality of life in dystonia, going above ...
Julie Ann Kristy L, Torres +1 more
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With the emergence of quality of life measures as an indicator for the impact of medical and surgical interventions in dystonia, focus has shifted toward unraveling the pathophysiology and neuroanatomical basis of the "nonmotor symptoms" (NMS). To date, the NMS are now recognized as the greater determinant of quality of life in dystonia, going above ...
Julie Ann Kristy L, Torres +1 more
openaire +2 more sources
The nonmotor symptoms of Parkinson's disease—An overview†
Movement Disorders, 2010AbstractNonmotor symptoms (NMS) are very common in Parkinson's disease (PD) and may result in significant disability. The increased focus on these important clinical features represents a major advance in the care of PD patients. In this article, we provide an overview of recent developments in the field.
Shen-Yang Lim, Anthony Lang
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Nonmotor Symptoms in Parkinson’s Disease
Der Nervenarzt, 2018Parkinson's disease is a neurodegenerative disease that affects the peripheral and central nervous system. In addition to the motor symptoms, a large number of nonmotor symptoms, which are of high clinical relevance, occur in all disease stages. Particular attention has been paid to neuropsychiatric and autonomic disorders in recent years.
D Vasudevan, A Thaseen, Tushar VP
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Comorbidity of the nonmotor symptoms of Parkinson's disease
Movement Disorders, 2001AbstractMany patients with Parkinson's disease (PD) have clinically significant anxiety, depression, fatigue, sleep disturbance, or sensory symptoms. The comorbidity of these nonmotor symptoms and their relationship to PD severity has not been extensively evaluated. Ninety‐ nine nondemented PD patients were evaluated with the following battery of tests:
L M, Shulman +3 more
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The Gut and Nonmotor Symptoms in Parkinson's Disease
2017Gastrointestinal (GI) symptoms are one of the most common nonmotor symptoms (NMS) in patients with Parkinson's disease (PD) involving the whole GI tract (GIT) and being evident throughout the whole course of the disease. Furthermore, constipation serves as a risk factor for PD as well as an early prodromal NMS of PD.
Lisa, Klingelhoefer, Heinz, Reichmann
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Deep Brain Stimulation and Nonmotor Symptoms
2017Deep brain stimulation (DBS) is currently the treatment of choice for advanced Parkinson's disease (PD). Several brain targets, including the subthalamic nucleus and the globus pallidus internus, have been successfully employed, with excellent motor outcomes.
Elliot, Hogg +3 more
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Nonmotor Symptoms in Huntington Disease
2017Huntington disease (HD) is characterized by the triad of motor abnormalities, cognitive dysfunction, and behavioral changes. The aim of this chapter is to describe the frequency, clinical features, and management of behavioral and cognitive dysfunction in HD.
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Genes and Nonmotor Symptoms in Parkinson's Disease
2017Published data on genetic risk factors of nonmotor symptoms (NMS) are relatively lacking since the first mutation responsible for Parkinson's disease (PD) being reported in 1996. This chapter provides a concise summary of genetic links to common individual NMS such as cognitive impairment, depression, psychosis, olfactory dysfunction, pain, and sleep ...
Lim E.-W., Tan E.-K.
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Measurement of Nonmotor Symptoms in Clinical Practice
2017Nonmotor symptoms constitute a prominent part of Parkinson's disease manifestations. They are present since the first phases of the disease, increase their number and severity with disease progression, and importantly impact on patients' health and quality of life, caregivers' burden, and social resources.
Pablo, Martinez-Martin +4 more
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Biomarkers of Nonmotor Symptoms in Parkinson's Disease
2017Biomarkers are helpful for early diagnosis, assessment of disorder severity, prognosis, and prediction of response to therapy. Given that early therapeutic intervention may be useful in forestalling or slowing neurodegenerative conditions, employing reliable biomarkers to identify asymptomatic individuals who are destined to develop clinical Parkinson ...
Takuya, Konno +3 more
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