Results 51 to 60 of about 3,213 (201)
Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. [PDF]
, 2020 Male factor infertility is a problem in today's society but many underlying causes are still unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) knockout mouse line (SCCx43KO) has provided a translational model ...
Behr, Rüdiger +10 more
core +1 more source
Systematic analysis of protein interaction network associated with azoospermia [PDF]
, 2016 Non-obstructive azoospermia is a severe infertility factor. Currently, the etiology of this condition remains elusive with several possible molecular pathway disruptions identified in the post-meiotic spermatozoa.
Sabetian, S., Shamsir, M. S.
core +2 more sources
Semen parameters can be predicted from environmental factors and lifestyle using artificial intelligence methods [PDF]
, 2013 Fertility rates have dramatically decreased in the last two decades, especially in men. It has been described that environmental factors as well as life habits may affect semen quality.
Gil, David +4 more
core +2 more sources
Meiotic recombination and male infertility: from basic science to clinical reality? [PDF]
, 2011 Infertility is a common problem that affects approximately 15% of the population. Although many advances have been made in the treatment of infertility, the molecular and genetic causes of male infertility remain largely elusive. This review will present
Hann, Michael C. +2 more
core +1 more source
iMetaOmics, EarlyView.SPARK is an interactive platform hosting 189,232 human testicular single‐cell transcriptomes across normal and infertile conditions. It enables automated, code‐free analysis and visualization, providing a powerful resource to explore cellular and molecular dynamics in male reproduction and infertility.
Lina Cui +9 more
wiley +1 more source
Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
Advanced Science, Volume 13, Issue 4, 19 January 2026.To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source
Journal of Human Reproductive Sciences, 2015 Spermatids are the earliest male germ cells with haploid set of chromosomes. Spermatid injection was introduced in human assisted reproduction for the treatment of men with non-obstructive azoospermia.
Geeta Goswami +2 more
doaj +1 more source
Update on the Management of Non-Obstructive Azoospermia: Current Evidence and Unmet Needs [PDF]
, 2022 Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men.
core +1 more source
Andrologia, Volume 2026, Issue 1, 2026.Background The impact of partial azoospermia factor c (AZFc) deletions and deleted in azoospermia (DAZ) deletions located on the long arm of the Y chromosome (Yq) on the risk of oligozoospermia and azoospermia remains a subject of debate. Objective This study aims to investigate the prevalence of partial AZFc deletions and DAZ deletions in infertile ...
Lanyan Tang +9 more
wiley +1 more source
Focus Issue on Male Infertility
Advances in Urology, 2012 Male infertility problems can occur when sperms are limited in number or function. In this paper, we describe the clinical evaluation of male infertility. A detailed history, physical examination, and basic semen analysis are required.
Hideyuki Kobayashi +2 more
doaj +1 more source