Results 51 to 60 of about 9,757 (189)
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Hormonal Treatment of Men with Nonobstructive Azoospermia: What Does the Evidence Suggest?
Hormonal stimulation of spermatogenesis prior to surgery has been tested by some authors to maximize the sperm retrieval yield in patients with nonobstructive azoospermia.
Giovanni M. Colpi, Ettore Caroppo
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Spermatids are the earliest male germ cells with haploid set of chromosomes. Spermatid injection was introduced in human assisted reproduction for the treatment of men with non-obstructive azoospermia.
Geeta Goswami +2 more
doaj +1 more source
Correlation of serum FSH and rate of testicular sperm retrieval in non-obstructive azoospermia
Background: Sperm retrieval from men with azoospermia has evolved in recent times, providing patient hope for fulfilling their dream of having their own genetic child through testicular sperm extraction followed by intracytoplasmic sperm injection (TESE ...
Kaberi Banerjee +2 more
doaj +1 more source
Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede +11 more
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Focus Issue on Male Infertility
Male infertility problems can occur when sperms are limited in number or function. In this paper, we describe the clinical evaluation of male infertility. A detailed history, physical examination, and basic semen analysis are required.
Hideyuki Kobayashi +2 more
doaj +1 more source
Objectives: Men with nonobstructive azoospermia may father a child through intracytoplasmic injection of testicular sperms. This can result in transmission of genetic defects such as Y chromosome microdeletions which primarily caused the infertility and ...
Rajeev Kumar +3 more
doaj +1 more source
A multiplex tissue resource for high‐resolution spatial protein profiling in the Human Protein Atlas
Abstract Spatially resolved protein expression is essential for understanding tissue organization, cellular specialization, and protein function. The open‐access Human Protein Atlas database (www.proteinatlas.org) has generated an extensive antibody‐based tissue resource for a majority of the human protein‐coding genes using conventional ...
Borbala Katona +9 more
wiley +1 more source
Mutational analysis of the GATA4 gene in Chinese men with nonobstructive azoospermia
As a crucial transcription factor for spermatogenesis, GATA-binding protein 4 (GATA4) plays important roles in the functioning of Sertoli and Leydig cells.
Xu Zhang +8 more
doaj +1 more source
EDITORIAL COMMENT There is a growing body of data in the literature that patients with nonobstructive azoospermia (NOA) may benefit from varicocele repair in terms of sperm recovery at testicular sperm extraction or presence of sperm in the ejaculate.
Emre Bakırcıoğlu
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