Microdissection testicular sperm extraction causes spermatogenic alterations in the contralateral testis [PDF]
, 2010 Testicular sperm extraction (TESE) associated with intracytoplasmic sperm injection has allowed many men presenting non-obstructive azoospermia to achieve fatherhood.
Azeredo-Oliveira, Maria Tercilia Vilela de +4 more
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Systematic analysis of protein interaction network associated with azoospermia [PDF]
, 2016 Non-obstructive azoospermia is a severe infertility factor. Currently, the etiology of this condition remains elusive with several possible molecular pathway disruptions identified in the post-meiotic spermatozoa.
Sabetian, S., Shamsir, M. S.
core +2 more sources
Meiotic recombination and male infertility: from basic science to clinical reality? [PDF]
, 2011 Infertility is a common problem that affects approximately 15% of the population. Although many advances have been made in the treatment of infertility, the molecular and genetic causes of male infertility remain largely elusive. This review will present
Hann, Michael C. +2 more
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Semen parameters can be predicted from environmental factors and lifestyle using artificial intelligence methods [PDF]
, 2013 Fertility rates have dramatically decreased in the last two decades, especially in men. It has been described that environmental factors as well as life habits may affect semen quality.
Gil, David +4 more
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Update on the Management of Non-Obstructive Azoospermia: Current Evidence and Unmet Needs [PDF]
, 2022 Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men.
core +1 more source
An miR-200 Cluster on Chromosome 23 Regulates Sperm Motility in Zebrafish [PDF]
, 2018 Besides its well-documented roles in cell proliferation, apoptosis, and carcinogenesis, the function of the p53-microRNA axis has been recently revealed in the reproductive system.
Dan, Cheng +6 more
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Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
Advanced Science, Volume 13, Issue 4, 19 January 2026.To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source
Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa [PDF]
, 2017 It has been suggested that the energy required for sperm motility is produced by oxidative phosphorylation while glycolysis seems to be an important source for ATP transmission along the flagellum.
Coltrinari, Giulia +6 more
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Non-obstructive azoospermia: current and future perspectives. [PDF]
, 2021 Infertility affects 1 in 6 couples, and male factor infertility has been implicated as a cause in 50% of cases. Azoospermia is defined as the absence of spermatozoa in the ejaculate and is considered the most extreme form of male factor infertility ...
Jayasena, Channa N +3 more
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Update and new advances in fertility preservation and cancer
CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 602-629, November/December 2025.Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility.
Gwendolyn P. Quinn +11 more
wiley +1 more source