Results 41 to 50 of about 724,098 (319)

Semi-parametric regression: Efficiency gains from modeling the nonparametric part

open access: yes, 2011
It is widely admitted that structured nonparametric modeling that circumvents the curse of dimensionality is important in nonparametric estimation. In this paper we show that the same holds for semi-parametric estimation.
Mammen, Enno   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

An R Package Implementation for Statistical Modeling of Emergence Curves in Weed Science

open access: yesProceedings, 2018
Over the last few years, the research group MODES has carried out a research line (in collaboration with researchers from the Sustainable Agriculture Institute of the CSIC in Córdoba) on statistical modeling in weed science. One of the aspects dealt with
Daniel Barreiro-Ures   +2 more
doaj   +1 more source

Nonparametric dynamic modeling [PDF]

open access: yesMathematical Biosciences, 2017
Challenging as it typically is, the estimation of parameter values seems to be an unavoidable step in the design and implementation of any dynamic model. Here, we demonstrate that it is possible to set up, diagnose, and simulate dynamic models without the need to estimate parameter values, if the situation is favorable.
Faraji, Mojdeh, Voit, Eberhard O.
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Factors related to psychopathological symptoms of female inmates of a prison in Lima

open access: yesRevista Española de Sanidad Penitenciaria, 2019
Objectives: The objective is to know the relationship between age, time of incarceration, juridical situation, activity in prison, penitentiary classification and having or not children under eighteen years old, with the incidence of psychopathological ...
S Esteban-Febres   +4 more
doaj   +1 more source

Nonparametric incidence estimation and bootstrap bandwidth selection in mixture cure models [PDF]

open access: yesComputational Statistics & Data Analysis
A completely nonparametric method for the estimation of mixture cure models is proposed. A nonparametric estimator of the incidence is extensively studied and a nonparametric estimator of the latency is presented. These estimators, which are based on the
Ana L´opez-Cheda   +3 more
semanticscholar   +1 more source

Nonparametric curve alignment [PDF]

open access: yes2009 IEEE International Conference on Acoustics, Speech and Signal Processing, 2009
4 pages, IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP ...
Mattar, MA, Ross, MG, Learned-Miller, EG
openaire   +3 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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