Results 51 to 60 of about 724,098 (319)

Pointwise universal consistency of nonparametric linear estimators [PDF]

, 2004
This paper presents sufficient conditions for pointwise universal consistency of nonparametric delta estimators.
Vidal-Sanz, Jose M.
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Measurement of Technical Efficiency of the Health-care Sector in Assam: An Application of Nonparametric Method

Indian Journal of Public Health
The study has used a nonparametric method to estimate the technical efficiency of health-care sector in the substate level of Assam. The study is based on secondary data for the year 2018–2019.
Arup Deka, Ratul Mahanta
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Simultaneous optimization of shape and topology for solid structure (Proposal of a topology optimization method with variable design domain)

Nihon Kikai Gakkai ronbunshu
Since the optimization results obtained by topology optimization depend on the size of the design domain, it is desirable to optimize the design domain as well during topology optimization.
Daiki YAMANE, Masatoshi SHIMODA
doaj   +1 more source

Nonparametric Estimates of Low Bias

Revstat Statistical Journal, 2012
We consider the problem of estimating an arbitrary smooth functional of k ≥ 1 distribution functions (d.f.s) in terms of random samples from them. The natural estimate replaces the d.f.s by their empirical d.f.s. Its bias is generally ∼ n−1 , where n is
Christopher S. Withers , Saralees Nadarajah   +1 more
doaj   +1 more source

Time-uniform, nonparametric, nonasymptotic confidence sequences [PDF]

Annals of Statistics, 2018
A confidence sequence is a sequence of confidence intervals that is uniformly valid over an unbounded time horizon. Our work develops confidence sequences whose widths go to zero, with nonasymptotic coverage guarantees under nonparametric conditions.
Steven R. Howard, Aaditya Ramdas, Jon D. McAuliffe, J. Sekhon   +3 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Mortality Forecasting: How Far Back Should We Look in Time?

Risks, 2019
Extrapolative methods are one of the most commonly-adopted forecasting approaches in the literature on projecting future mortality rates. It can be argued that there are two types of mortality models using this approach.
Han Li, Colin O’Hare
doaj   +1 more source

Public Spending Efficiency in the OECD: Benchmarking Health Care, Education, and General Administration

Review of Economic Perspectives, 2020
In many OECD countries, changes in demography and health conditions are putting pressure on public finance. To prevent further expansion of government spending as a percentage of GDP, public spending efficiency will need to be raised.
Dutu Richard, Sicari Patrizio
doaj   +1 more source