Results 41 to 50 of about 263,946 (269)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Measurement of Technical Efficiency of the Health-care Sector in Assam: An Application of Nonparametric Method

Indian Journal of Public Health
The study has used a nonparametric method to estimate the technical efficiency of health-care sector in the substate level of Assam. The study is based on secondary data for the year 2018–2019.
Arup Deka, Ratul Mahanta
doaj   +1 more source

Bandwidth Selection in Nonparametric Regression with Large Sample Size

Proceedings, 2018
In the context of nonparametric regression estimation, the behaviour of kernel methods such as the Nadaraya-Watson or local linear estimators is heavily influenced by the value of the bandwidth parameter, which determines the trade-off between bias and ...
Daniel Barreiro-Ures, Ricardo Cao, Mario Francisco-Fernández   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Distribution and Quantiles of Sample Autocovariances and Autocorrelations of Sample Moments from a Stationary Process

Axioms
This paper gives expansions for the distribution, density and quantiles of any estimate that is a smooth function of the sample cross-moments of a stationary process.
Christopher Stroude Withers
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Simultaneous optimization of shape and topology for solid structure (Proposal of a topology optimization method with variable design domain)

Nihon Kikai Gakkai ronbunshu
Since the optimization results obtained by topology optimization depend on the size of the design domain, it is desirable to optimize the design domain as well during topology optimization.
Daiki YAMANE, Masatoshi SHIMODA
doaj   +1 more source

Spatially Dependent Bayesian Modeling of Geostatistics Data and Its Application for Tuberculosis (TB) in China

Mathematics, 2023
Geostatistics data in regions always have highly spatial heterogeneous, yet the regional features of the data itself cannot be ignored. In this paper, a novel latent Bayesian spatial model is proposed, which incorporates the spatial dependence of ...
Zongyuan Xia, Bo Tang, Long Qin, Huiguo Zhang, Xijian Hu   +4 more
doaj   +1 more source

Nonparametric analysis of covariance [PDF]

The Annals of Statistics, 2001
In the problem of testing the equality of k regression curves from independent samples we discuss three methods using nonparametric estimation techniques of the regression function. The first test is based on a linear combination of estimators for the integrated variance function in the individual samples and in the combined sample. The second approach
Dette, Holger, Neumeyer, Natalie
openaire   +4 more sources

Comparison the Robust Estimators Nonparametric of Nonparametric Regressions

Tikrit Journal of Pure Science, 2023
In order to get rid of or reduce the abnormal values ​​of some phenomena that may be the reason for not obtaining the desired results. This makes us to get conclusions far from reality for the phenomenon we are studying. That the traditional nonparametric estimators are very sensitive to anomalous values, which prompted us to use the fortified ...
Ali Fadhil Abduljabbar, Afrah Mohammed Kadhim   +1 more
openaire   +2 more sources