Results 41 to 50 of about 369,804 (310)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Nonparametric multiple comparisons [PDF]

Behavior Research Methods, 2019
Nonparametric multiple comparisons are a powerful statistical inference tool in psychological studies. In this paper, we review a rank-based nonparametric multiple contrast test procedure (MCTP) and propose an improvement by allowing the procedure to accommodate various effect sizes.
Kimihiro Noguchi, Riley S. Abel, Fernando Marmolejo-Ramos, Frank Konietschke   +3 more
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Measurement of Technical Efficiency of the Health-care Sector in Assam: An Application of Nonparametric Method

Indian Journal of Public Health
The study has used a nonparametric method to estimate the technical efficiency of health-care sector in the substate level of Assam. The study is based on secondary data for the year 2018–2019.
Arup Deka, Ratul Mahanta
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The Distribution and Quantiles of Sample Autocovariances and Autocorrelations of Sample Moments from a Stationary Process

Axioms
This paper gives expansions for the distribution, density and quantiles of any estimate that is a smooth function of the sample cross-moments of a stationary process.
Christopher Stroude Withers
doaj   +1 more source

Comparison of Parametric and Nonparametric Forecasting Methods for Daily COVID-19 Cases in Malaysia

JOIV: International Journal on Informatics Visualization, 2023
Numerous research studies are currently examining various measures to control the transmission of COVID-19. One essential task in this regard is predicting or forecasting the number of infected individuals.
I Made Artha Agastya, Afrig Aminuddin
doaj   +1 more source

Nonparametric analysis of covariance [PDF]

The Annals of Statistics, 2001
In the problem of testing the equality of k regression curves from independent samples we discuss three methods using nonparametric estimation techniques of the regression function. The first test is based on a linear combination of estimators for the integrated variance function in the individual samples and in the combined sample. The second approach
Dette, Holger, Neumeyer, Natalie
openaire   +4 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Simultaneous optimization of shape and topology for solid structure (Proposal of a topology optimization method with variable design domain)

Nihon Kikai Gakkai ronbunshu
Since the optimization results obtained by topology optimization depend on the size of the design domain, it is desirable to optimize the design domain as well during topology optimization.
Daiki YAMANE, Masatoshi SHIMODA
doaj   +1 more source