Results 61 to 70 of about 724,098 (319)

How to Measure Galaxy Star Formation Histories. II. Nonparametric Models [PDF]

open access: yesAstrophysical Journal, 2018
Nonparametric star formation histories (SFHs) have long promised to be the “gold standard” for galaxy spectral energy distribution (SED) modeling as they are flexible enough to describe the full diversity of SFH shapes, whereas parametric models rule out
J. Leja   +4 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Nonparametric Independence Screening in Sparse Ultra-High Dimensional Additive Models [PDF]

open access: yes, 2010
A variable screening procedure via correlation learning was proposed Fan and Lv (2008) to reduce dimensionality in sparse ultra-high dimensional models. Even when the true model is linear, the marginal regression can be highly nonlinear.
Fan, Jianqing, Feng, Yang, Song, Rui
core   +1 more source

Specification testing in nonlinear and nonstationary time series autoregression

open access: yes, 2009
This paper considers a class of nonparametric autoregressive models with nonstationarity. We propose a nonparametric kernel test for the conditional mean and then establish an asymptotic distribution of the proposed test. Both the setting and the results
Gao, Jiti   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Adjusted Empirical Likelihood Method in the Presence of Nuisance Parameters with Application to the Sharpe Ratio

open access: yesEntropy, 2018
The Sharpe ratio is a widely used risk-adjusted performance measurement in economics and finance. Most of the known statistical inferential methods devoted to the Sharpe ratio are based on the assumption that the data are normally distributed.
Yuejiao Fu   +2 more
doaj   +1 more source

Conjugate Projective Limits [PDF]

open access: yes, 2011
We characterize conjugate nonparametric Bayesian models as projective limits of conjugate, finite-dimensional Bayesian models. In particular, we identify a large class of nonparametric models representable as infinite-dimensional analogues of exponential
Orbanz, Peter
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Plug-in Bandwidth Selection for Kernel Density Estimation with Discrete Data

open access: yesEconometrics, 2015
This paper proposes plug-in bandwidth selection for kernel density estimation with discrete data via minimization of mean summed square error. Simulation results show that the plug-in bandwidths perform well, relative to cross-validated bandwidths, in ...
Chi-Yang Chu   +2 more
doaj   +1 more source

Online Nonparametric Anomaly Detection based on Geometric Entropy Minimization

open access: yes, 2017
We consider the online and nonparametric detection of abrupt and persistent anomalies, such as a change in the regular system dynamics at a time instance due to an anomalous event (e.g., a failure, a malicious activity).
Yilmaz, Yasin
core   +1 more source

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