Results 101 to 110 of about 607,794 (304)

A Nonparametric Search for Information Effects from USDA Reports

open access: yesJournal of Agricultural and Resource Economics, 2015
Two nonparametric tests are employed to investigate the potential information value of USDA crop and livestock reports. If daily returns on days that reports are released (announcement days) differ when compared to non-announcement days for a sizeable ...
Jeffrey Dorfmann, Berna Karali
doaj   +1 more source

PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR‐T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
This study shows that a PARP inhibitor combined with anlotinib, administered as bridging therapy, preconditions the tumor microenvironment to enhance the infiltration and antitumor activity of subsequently infused CAR‐T cells across preclinical ovarian cancer models, supporting bridging therapy as a promising strategy to address limited CAR‐T cell ...
Huayi Li   +20 more
wiley   +1 more source

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

open access: yesAdvanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song   +9 more
wiley   +1 more source

A Nonparametric Approach to Evaluating Inflation-Targeting Regimes [PDF]

open access: yes
We use a variety of nonparametric test statistics to evaluate the inflation- targeting regimes of Australia, Canada, New Zealand, Sweden and the UK. We argue that a sensible approach of evaluation must rely on a variety of methods, among them parametric ...
Weshah Razzak, Rabie Nasser
core  

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Optimal input signal design for closed loop aircraft flutter model analysis

open access: yesScientific Reports
Input signal design is very important in academy and practice, as it affects the estimation accuracy and control performance. This paper extends our previous open loop aircraft flutter model analysis to more general closed loop case, as closed loop ...
Wang Jianhong
doaj   +1 more source

Treatment recommendation and parameter estimation under single-index contrast function

open access: yesStatistical Theory and Related Fields, 2017
In this article, we consider a semiparametric model for contrast function which is defined as the conditional expected outcome difference under comparative treatments.
Cui Xiong, Menggang Yu, Jun Shao
doaj   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han   +24 more
wiley   +1 more source

Nonparametric Efficiency Estimation in Stochastic Environments (II) [PDF]

open access: yes
We consider the issues of noise-to-signal estimation, finite sample performance andhypothesis testing for the nonparametric efficiency estimation technique proposed inCherchye, L., T. Kuosmanen and G. T. Post (2001) 'Nonparametric efficiencyestimation in
Post, G.T., Cherchye, L.
core  

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

open access: yesAdvanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang   +14 more
wiley   +1 more source

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