Results 161 to 170 of about 50,057 (258)

Disabling posttranscriptional regulation of AGO2 results in enhanced viral resistance

New Phytologist, EarlyView.
Márta Ludman, Károly Fátyol
wiley   +1 more source

SnapShot: Nonsense-Mediated mRNA Decay

Cell, 2011
Durand, Sébastien, Lykke-Andersen, Jens
openaire   +2 more sources

De novo variants disturbing the transactivation capacity of POU3F3 cause a characteristic neurodevelopmental disorder

, 2019
POU3F3, also referred to as Brain-1, is a well-known transcription factor involved in the development of the central nervous system, but it has not previously been associated with a neurodevelopmental disorder.
Au, C., Baker, S., Bergstrom, K., Bodek, S., Brunner, H., Cunniff, C., Dentici, M., Derizioti, P., Faivre, L., Firth, H., Fisher, S., Gilissen, C., Iglesias, A., Izumi, K., Kleefstra, T., Kroes, H., Lachmeijer, A., Leonard, J., Maas, S., Matsumoto, N., Miyake, N., Niceta, M., Okamoto, N., Pfundt, R., Philippe, C., Powis, Z., Shinde, D., Snijders Blok, L., Tang, S., Tartaglia, M., Tayoun, A., Tomkins, S., Van Gassen, K., Venselaar, H., Vitobello, A., Wiel, L., Wojcik, M., Õunap, K.   +37 more
core   +1 more source

p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells [PDF]

, 2017
Cheruiyot, Abigael, Flanagan, Kevin C., Nickless, Andrew, Piwnica-Worms, David, Stewart, Sheila A., You, Zhongsheng   +5 more
core   +2 more sources

The interplay between mRNA translation and nonsense-mediated decay in AUG-proximal nonsense-mutated transcripts [PDF]

, 2014
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and rapidly degrades mRNAs containing premature termination codons (PTC).
Romão, Luísa
core  

Loss of function mutations in RP1 are responsible for retinitis pigmentosa in consanguineous familial cases. [PDF]

, 2016
PurposeThis study was undertaken to identify causal mutations responsible for autosomal recessive retinitis pigmentosa (arRP) in consanguineous families.MethodsLarge consanguineous families were ascertained from the Punjab province of Pakistan.
Akram, Javed, Ali, Shahbaz, Assir, Muhammad Zaman, Ayyagari, Radha, Gottsch, Alexander DH, Hejtmancik, J Fielding, Kabir, Firoz, Khan, Shaheen N, Naeem, Muhammad Asif, Riazuddin, S Amer, Riazuddin, Sheikh, Ullah, Inayat   +11 more
core   +1 more source

The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense‐mediated mRNA decay

EMBO Journal, 2001
Hervé Le Hir, D. Gatfield, E. Izaurralde, M. Moore   +3 more
semanticscholar   +1 more source

Nonsense-mediated mRNA decay in health and disease.

Human Molecular Genetics, 1999
P. Frischmeyer, H. Dietz
semanticscholar   +1 more source

Nonsense-mediated mRNA decay in collagen X

, 2010
Genetic disorders are a major cause of human disability and disease. It has been estimated that 5-10% of the population is affected by an inherited disorder during their lifetime, and a startling 70% of pediatric admissions involve a genetic component.
openaire   +1 more source

Nonsense-mediated mRNA decay in humans at a glance

Journal of Cell Science, 2016
Tatsuaki Kurosaki, L. Maquat
semanticscholar   +1 more source