Results 201 to 210 of about 141,024 (299)

OsFKBP20‐1b stabilizes OsUPF1 and OsUPF2 to promote the degradation of aberrant mRNAs during dehydration stress

Journal of Integrative Plant Biology, EarlyView.
The rice protein OsFKBP20‐1b protects key RNA‐surveillance factors from breakdown, so they can better eliminate defective messages. This RNA quality‐control boost reduces errors and helps plants survive drought, revealing a link between RNA control and drought tolerance.
Haemyeong Jung, Hyun Ji Park, Seung Hee Jo, Ki‐Hong Jung, Choonkyun Jung, Hye Sun Cho   +5 more
wiley   +1 more source

Optimized TadA‐derived base editors efficiently manipulate mRNA splicing by A‐to‐G and C‐to‐K editing in potato

Journal of Integrative Plant Biology, EarlyView.
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen, Yan Zhang, Jiuzhou Deng, Lumin Zhang, Huiying Zhou, Yaxin Duan, Enle Xiao, Guangtao Zhu, Chunzhi Zhang   +8 more
wiley   +1 more source

Combinatorial biosynthesis of novel gentamicin derivatives with nonsense mutation readthrough activity and low cytotoxicity. [PDF]

Front Pharmacol
Yang L, Zhai H, Tian T, Liu B, Ni X, Xia H.   +5 more
europepmc   +1 more source

The First Heterozygous <i>TWNK</i> Nonsense Mutation Associated with Progressive External Ophthalmoplegia: Evidence for a New Piece in the Puzzle of Mitochondrial Diseases. [PDF]

Biomolecules
Lopergolo D, Berti G, Gallus GN, Bianchi S, Santorelli FM, Malandrini A, De Stefano N.   +6 more
europepmc   +1 more source

Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus, Ulrike Wieland, Steffi Silling, Julia Hyun, Milan Vidakovic, Frank Oellig, Alexander Kreuter, Valentina Laura Müller   +7 more
wiley   +1 more source

Case Report: A <i>FBN1</i> frameshift-and-nonsense mutation and aortic dissection in Marfan syndrome. [PDF]

Front Cardiovasc Med
Su C, Zeng L, Lu H, Wang Z, Wei M.
europepmc   +1 more source

Cyclophilin A‐mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes

New Phytologist, EarlyView.
Summary In most legume‐rhizobium symbioses, rhizobial colonization occurs through host‐derived intracellular infection threads, which enable rhizobial recruitment while presumably modulating the host immune system to prevent rejection. To investigate post‐translational regulation of immune responses during rhizobial infection, we focused on Cyclophilin
Takashi Goto, Kasper Røjkjær Andersen, Masaru Bamba, Shusei Sato, Masayuki Sugawara, Kiwamu Minamisawa, Masayoshi Kawaguchi, Jens Stougaard, Yasuyuki Kawaharada   +8 more
wiley   +1 more source

A heterozygous nonsense mutation in the FGB gene (c.1299G > A) causes congenital fibrinogen disorder across four consecutive generations. [PDF]

Thromb J
Chen W, Hu J.
europepmc   +1 more source

“Strange can be quite normal”: How the environmental crisis becomes present in Han Kang's and Samanta Schweblin's “constructively alienating” environmental fiction

Orbis Litterarum, EarlyView.
Abstract This article presents the concept “constructive alienation” as a response to the oversaturation of apocalyptic environmental fiction that has contributed to deep‐seated desensitization toward the climate crisis, resulting in crisis of imagination (Ghosh, The Great Derangement: Climate change and the unthinkable, 2016; Solnit, If you win the ...
Agnethe Brounbjerg Bennedsgaard
wiley   +1 more source

Novel nonsense mutation in the TCOF1 gene associated with treacher collins syndrome: A case report. [PDF]

Sci Prog
Cadena-Ullauri S, Tamayo-Trujillo R, Paz-Cruz E, Guevara-Ramírez P, Ruiz-Pozo VA, Cuenca FA, Zambrano AK.   +6 more
europepmc   +1 more source