Results 211 to 220 of about 141,024 (299)

Enhancing CRISPR/Cas‐Mediated Gene Knockout With Short Non‐Homologous Oligonucleotides

Plant Biotechnology Journal, EarlyView.
ABSTRACT Chlamydomonas reinhardtii is a model green microalga that has great industrial potential as a sustainable bio‐factory for recombinant protein and high‐value chemical production. Efficient genome editing tools are required to redesign this organism for synthetic biology applications. CRISPR‐Cas editing technologies have already been adapted for
Yen Peng Chew, Aron Ferenczi, Marie Dannay, Cristina Ponce‐Lilly, Adam Kovac, Dávid Tóth, Szilvia Z. Tóth, Attila Molnar   +7 more
wiley   +1 more source

Marked improvement in severe pulmonary arterial hypertension following airway infection in a patient with a heterozygous BMP9 nonsense mutation: a case report. [PDF]

Eur Heart J Case Rep
Sakurai M, Yamaguchi Y, Takasawa K, Hosokawa S, Ishii T.   +4 more
europepmc   +1 more source

Nonsense mutations causing premature translation termination [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

CYLD Cutaneous Syndrome: Report of a New Splicing Pathogenic Variant and Additional Evidence Supporting the Absence of Genotype–Phenotype Correlation

International Journal of Dermatology, EarlyView.
Agathe Hercent, Adrien Borgel, Jerôme Lamoril, Florent Grange, Frédérique Carré‐Pigeon, Caroline Kannengiesser, Dimitri Tchernitchko   +6 more
wiley   +1 more source

Engineering a Gibberellin‐Switchable Dual‐Use Line Based on Ent‐Kaurene Oxidase Gene ZmKO1 Enables Two‐Line Hybrid Seed Production in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Male‐sterile systems are pivotal for maize hybrid seed production, yet existing systems are constrained by significant limitations. Here, we identified a novel single‐gene‐controlled recessive genic male sterility (GMS) mutant, defective in filament elongation 1 (def1), which exhibits non‐elongated filaments, unopened glumes, and non‐exserted ...
Chuan Li, Siyu Wang, Yong Xiang, Tao Yu, Rujun Wei, Wenqian Mei, Xiaowei Liu, Peng Yuan, Hongyang Yi, Shufeng Zhou, Chao Xia, Moju Cao, Hai Lan   +12 more
wiley   +1 more source

A novel nonsense mutation in <i>SCAF4</i> associated with fliedner-zweier syndrome: a case report and review of the literature. [PDF]

Front Genet
Chen Z, Zhao J, Fan X, Xuan X, Zhao X.
europepmc   +1 more source

Spatial Regulation of Silicon Accumulation in Peduncle Confers Sheathed Spike in Barley

Plant Biotechnology Journal, EarlyView.
ABSTRACT Peduncle, the uppermost internode in cereals, connects the stem to the inflorescence and is critical for the transport of water, nutrients and photosynthetic assimilates. While peduncle length associates with plant height and its elongation is primarily regulated by phytohormones, we report a previously unrecognized mechanism involving the ...
Wenxue Wu, Congcong Jiang, Guangqi Gao, Namiki Mitani‐Ueno, Yu Guo, Jinhong Kan, Yehui Xiong, Martin Mascher, Zhongfu Ni, Jian Feng Ma, Ke Wang, Ping Yang   +11 more
wiley   +1 more source

Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases. [PDF]

Nucleic Acids Res
Bhat SY, Bhattacharya A, Li H, Cui X, Lueck JD, Goldman YE, Cooperman BS.   +6 more
europepmc   +1 more source

A Water‐Saving Drought Survival Phenotype in a Wheat TILLING Mutant Involves Survival‐Biased Metabolic and Phosphorylation Reprogramming

Plant, Cell &Environment, EarlyView.
ABSTRACT Drought tolerance in crops often involves trade‐offs between water conservation, growth and reproduction. Understanding how water‐saving strategies are implemented at physiological and metabolic levels remains critical for improving crop performance under water‐limited conditions.
Ryosuke Mega, Shun‐ichiro Hirata, Kota Yamashita, Hinano Takase, Taishi Umezawa, Yasuko Watanabe, June‐Sik Kim, Tomoyuki Kosaka, Akihiro Nieda, Hisashi Tsujimoto   +9 more
wiley   +1 more source