Results 111 to 120 of about 160,452 (346)

NSAID-Induced Small Bowel Diaphragms and Strictures Diagnosed with Intraoperative Enteroscopy

open access: yesCanadian Journal of Gastroenterology, 2001
Nonsteroidal anti-inflammatory drugs are known to cause mucosal damage in the stomach and duodenum, which may lead to hemorrhage and perforation. However, these medications may also cause damage in the more distal small bowel.
Douglas A Shumaker   +2 more
doaj   +1 more source

Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. [PDF]

open access: yes, 2019
Objective:The interleukin-1 (IL-1) receptor antagonist anakinra is an effective, off-label option in acute gout flares, when conventional therapy options are narrowed.
Pedersen, Brian   +2 more
core  

Anti‐inflammatory and Gastroprotective Effects of the Chamaerops humilis L. (DOUM) Fruit Aqueous Extract in Experimental Models of Edema and Gastric Ulcer

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Chronic inflammation can lead to various diseases, including gastric ulcers, highlighting the need for effective therapeutic strategies. The traditional use of Chamaerops humilis in Moroccan folk medicine for treating gastrointestinal disorders underscores its potential as a valuable natural remedy.
Yasmina Jaouhari   +12 more
wiley   +1 more source

Risk of myocardial infarction with use of selected nonsteroidal anti-inflammatory drugs in spondyloarthritis patients [PDF]

open access: yes, 2017
BACKGROUND: Spondyloarthritis (SpA) is associated with increased risk of myocardial infarction (MI); the risk may be due to the underlying inflammatory disease, or also due to medications that increase MI risk, such as certain non-steroidal anti ...
Dubreuil, Maureen
core   +1 more source

Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou   +3 more
wiley   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

open access: yesChemMedChem, Accepted Article.
Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore   +5 more
wiley   +1 more source

A Randomized Phase 1 Study Evaluating Pharmacokinetics, Safety, and Tolerability of a High‐Concentration, Long‐Acting Cabotegravir Formulation in Adults Without HIV

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Long‐acting (LA) cabotegravir 200‐mg/mL (CAB200) injections are approved for HIV‐1 prevention and as a complete LA HIV‐1 treatment regimen with rilpivirine. A high‐concentration suspension formulation, cabotegravir 400 mg/mL (CAB400‐D), was developed to enable less frequent dosing and self‐administration. This phase 1, double‐blind, randomized
Kelong Han   +16 more
wiley   +1 more source

Early tumor response to intraarterial or intravenous administration of carboplatin to treat naturally occurring lower urinary tract carcinoma in dogs. [PDF]

open access: yes, 2015
BackgroundSurvival times and tumor responses associated with malignant neoplasia of the lower urinary tract are poor despite the vast array of current treatments.
Berent, AC   +8 more
core  

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