Results 11 to 20 of about 142,808 (332)

Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti‐Inflammatory Drugs

Clinical pharmacology and therapy, 2020
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are among the most commonly used analgesics due to their lack of addictive potential. However, NSAIDs have the potential to cause serious gastrointestinal, renal, and cardiovascular adverse events.
K. N. Theken, Craig R. Lee, L. Gong, K. Caudle, Christine M. Formea, A. Gaedigk, T. Klein, J. Agúndez, T. Grosser   +8 more
semanticscholar   +1 more source

Enhanced adsorptive removal of diclofenac sodium from aqueous solution by bentonite-supported nanoscale zero-valent iron

Arab Journal of Basic and Applied Sciences, 2021
Nano zero-valent iron-bentonite (B-nZVI) is an excellent composite for treating recalcitrant organic pollutants. In this study, B-nZVI was prepared via NaBH4 reduction method and characterized using different instruments including X-ray diffractometer ...
Saleh M. Sulaiman, Mohammed H. Al-Jabari
doaj   +1 more source

Not all (N)SAID and done: Effects of nonsteroidal anti‐inflammatory drugs and paracetamol intake on platelets

Research and Practice in Thrombosis and Haemostasis, 2020
Platelets are key mediators of hemostasis and thrombosis and can be inhibited by nonsteroidal anti‐inflammatory drugs (NSAIDs). As a result, platelet donors are temporarily deferred from donating if they have recently taken NSAIDs such as aspirin or ...
Ben Driver, Denese C. Marks, Dianne E. van derWal   +2 more
doaj   +1 more source

Experimental study of the antiulcer effect of cryopreserved placenta extract on a model of acetylsalicylic acid-induced ulcerogenesis

Current Issues in Pharmacy and Medical Sciences, 2022
Introduction. The gastrotoxicity of nonsteroidal anti-inflammatory drugs is a leading side effect that significantly limits their clinical use, among other types of their toxicity (nephrotoxicity, hepatotoxicity, cardiotoxicity, etc.).
Hladkykh Fedir Vol.
doaj   +1 more source

Progress in understanding hypersensitivity reactions to nonsteroidal anti‐inflammatory drugs

Allergy. European Journal of Allergy and Clinical Immunology, 2020
Nonsteroidal anti‐inflammatory drugs (NSAIDs), the medications most commonly used for treating pain and inflammation, are the main triggers of drug hypersensitivity reactions.
I. Doña, N. Pérez‐Sánchez, I. Eguiluz-Gracia, R. Muñoz-Cano, J. Bartra, M. Torres, J. Cornejo‐García   +6 more
semanticscholar   +1 more source

Nonsteroidal Anti-Inflammatory Drugs and Opioids in Postsurgical Dental Pain

Journal of dentistry research, 2020
Postsurgical dental pain is mainly driven by inflammation, particularly through the generation of prostaglandins via the cyclooxygenase system. Thus, it is no surprise that numerous randomized placebo-controlled trials studying acute pain following the ...
E. Hersh, P. Moore, T. Grosser, R. Polomano, J. Farrar, M. Saraghi, S.A. Juska, C. Mitchell, K. N. Theken   +8 more
semanticscholar   +1 more source

Duration of Symptom Relief and Early Trajectory of Adverse Events for Oral Nonsteroidal Antiinflammatory Drugs in Knee Osteoarthritis: A Systematic Review and Meta‐Analysis

Arthritis care & research, 2020
Despite an extensive body of research on nonsteroidal antiinflammatory drugs (NSAIDs) in osteoarthritis, the duration of their efficacy and timeline of adverse event (AE) onset have been understudied.
M. Osani, E. Vaysbrot, Mengyu Zhou, T. McAlindon, Raveendhara R. Bannuru   +4 more
semanticscholar   +1 more source

Nonsteroidal Anti‐inflammatory Use and LRRK2 Parkinson's Disease Penetrance

Movement Disorders, 2020
The penetrance of leucine rich repeat kinase 2 (LRRK2) mutations is incomplete and may be influenced by environmental and/or other genetic factors. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are known to reduce inflammation and may lower Parkinson's ...
Marta San Luciano, C. Tanner, Cheryl Meng, C. Marras, S. Goldman, A. Lang, E. Tolosa, B. Schüle, J. Langston, A. Brice, J. Corvol, S. Goldwurm, C. Klein, Simone Brockman, D. Berg, K. Brockmann, J. Ferreira, M. Tazir, G. Mellick, C. Sue, K. Hasegawa, E. Tan, S. Bressman, R. Saunders-Pullman   +23 more
semanticscholar   +1 more source

Avaliação de riscos teratogênicos em gestações expostas ao misoprostol Evaluation of the teratogenic risks in gestations exposed to misoprostol

Revista Brasileira de Ginecologia e Obstetrícia, 2010
OBJETIVOS: a tentativa de aborto mal sucedida com o uso do misoprostol (Cytotec®) sem indicação médica tem sido associada a malformações congênitas.
Emérita Sátiro Opaleye, Helena Lutéscia Luna Coelho, Lavínia Schüler-Faccini, Paulo César de Almeida, Elaine Cavalcante dos Santos, Ana Júlia Velozo Ribeiro, Fabrício da Silva Costa   +6 more
doaj   +1 more source

Genotoxic potential of nonsteroidal hormones [PDF]

Veterinarski Glasnik, 2015
Hormones are cellular products involved in the regulation of a large number of processes in living systems, and which by their actions affect the growth, function and metabolism of cells.
Topalović Dijana, Živković Lada, Đelić Ninoslav, Bajić Vladan, Čabarkapa Andrea, Jović Slavoljub, Spremo-Potparević Biljana   +6 more
doaj   +1 more source