Synaptic and Nonsynaptic Plasticity Approximating Probabilistic Inference [PDF]
Frontiers in Synaptic Neuroscience, 2014 The brain stores and retrieves information by initiating cascades of molecular changes that lead to a diverse repertoire of dynamical phenomena at higher levels of processing.
Philip Joseph Tully +6 more
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Failure of delayed nonsynaptic neuronal plasticity underlies age-associated long-term associative memory impairment [PDF]
BMC Neuroscience, 2012 Background Cognitive impairment associated with subtle changes in neuron and neuronal network function rather than widespread neuron death is a feature of the normal aging process in humans and animals.
Watson Shawn N +3 more
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Linking the Amyloid, Tau, and Mitochondrial Hypotheses of Alzheimer’s Disease and Identifying Promising Drug Targets [PDF]
Biomolecules, 2022 Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as Alzheimer’s disease (AD).
Zdeněk Fišar
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More than synaptic plasticity: role of nonsynaptic plasticity in learning and memory. [PDF]
Trends Neurosci, 2010 Mozzachiodi R, Byrne JH.
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Frontiers in Cellular Neuroscience, 2015 Learning and memory require alteration in number and strength of existing synaptic connections. Extracellular proteolysis within the synapses has been shown to play a pivotal role in synaptic plasticity by determining synapse structure, function, and ...
Tomasz eWójtowicz +3 more
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The nonsynaptic plasticity in Parkinson's disease: Insights from an animal model
Clinics, 2023 Mónica Viegas +11 more
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A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology
eLife, 2022 Neuroscience currently requires the use of antibodies to study synaptic proteins, where antibody binding is used as a correlate to define the presence, plasticity, and regulation of synapses. Gephyrin is an inhibitory synaptic scaffolding protein used to
Benjamin FN Campbell +4 more
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Non-synaptic Plasticity in Leech Touch Cells
Frontiers in Physiology, 2019 The role of Na+/K+-pumps in activity-dependent synaptic plasticity has been described in both vertebrates and invertebrates. Here, we provide evidence that the Na+/K+-pump is also involved in activity-dependent non-synaptic cellular plasticity in leech ...
Sonja Meiser +4 more
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About a snail, a toad and rodents: animal models for adaptation research
Frontiers in Endocrinology, 2010 Neural adaptation mechanisms have many similarities throughout the animal kingdom, enabling to study fundamentals of human adaptation in selected animal models with experimental approaches that are impossible to apply in man.
Eric W Roubos +5 more
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The role of astrocytes from synaptic to non-synaptic plasticity
Frontiers in Cellular NeuroscienceInformation storage and transfer in the brain require a high computational power. Neuronal network display various local or global mechanisms to allow information storage and transfer in the brain.
Rafael Sanz-Gálvez +8 more
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