Results 1 to 10 of about 270,619 (156)

Synaptic and Nonsynaptic Plasticity Approximating Probabilistic Inference [PDF]

Frontiers in Synaptic Neuroscience, 2014
The brain stores and retrieves information by initiating cascades of molecular changes that lead to a diverse repertoire of dynamical phenomena at higher levels of processing.
Philip Joseph Tully, Philip Joseph Tully, Philip Joseph Tully, Matthias H Hennig, Anders eLansner, Anders eLansner, Anders eLansner   +6 more
doaj   +9 more sources

More than synaptic plasticity: role of nonsynaptic plasticity in learning and memory. [PDF]

Trends Neurosci, 2010
Decades of research on the cellular mechanisms of memory have led to the widely held view that memories are stored as modifications of synaptic strength. These changes involve presynaptic processes, such as direct modulation of the release machinery, or postsynaptic processes, such as modulation of receptor properties.
Mozzachiodi R, Byrne JH.
europepmc   +9 more sources

Failure of delayed nonsynaptic neuronal plasticity underlies age-associated long-term associative memory impairment [PDF]

BMC Neuroscience, 2012
Background Cognitive impairment associated with subtle changes in neuron and neuronal network function rather than widespread neuron death is a feature of the normal aging process in humans and animals.
Watson Shawn N, Risling Tara E, Hermann Petra M, Wildering Willem C   +3 more
doaj   +8 more sources

The nonsynaptic plasticity in Parkinson's disease: Insights from an animal model

Clinics, 2023
The 6-OHDA nigro-striatal lesion model has already been related to disorders in the excitability and synchronicity of neural networks and variation in the expression of transmembrane proteins that control intra and extracellular ionic concentrations, such as cation-chloride cotransporters (NKCC1 and KCC2) and Na+/K+-ATPase and, also, to the glial ...
Mónica Viegas, Luiz Eduardo Canton Santos, Mayra C. Aarão, Samyra Giarola Cecílio, Joana M. Medrado, Arthur C. Pires, Antônio Márcio Rodrigues, Carla A. Scorza, Marcelo A. Moret, Josef Finsterer, Fúlvio A. Scorza, Antônio-Carlos G. de Almeida   +11 more
semanticscholar   +4 more sources

Nonsynaptic Plasticity Underlies a Compartmentalized Increase in Synaptic Efficacy after Classical Conditioning [PDF]

Current Biology, 2013
It is now well documented in both vertebrates and invertebrates that nonsynaptic as well as synaptic plasticity can be a substrate for long-term memory [1-4]. Little is known, however, about how learning-induced nonsynaptic plasticity can lead to compartmentalized presynaptic changes underlying specific memory traces while leaving other circuit ...
Е. С. Никитин, П. М. Балабан, György Kemenes   +2 more
semanticscholar   +4 more sources

Nonsynaptic NMDA Receptors Mediate Activity-Dependent Plasticity of Gap Junctional Coupling in the AII Amacrine Cell Network [PDF]

The Journal of Neuroscience, 2012
Many neurons are coupled by electrical synapses into networks that have emergent properties. In the retina, coupling in these networks is dynamically regulated by changes in background illumination, optimizing signal integration for the visual environment. However, the mechanisms that control this plasticity are poorly understood.
W. Wade Kothmann, E. Brady Trexler, Christopher M. Whitaker, Wei Li, Stephen C. Massey, John O’Brien   +5 more
semanticscholar   +4 more sources

Role of Delayed Nonsynaptic Neuronal Plasticity in Long-Term Associative Memory [PDF]

Current Biology, 2006
It is now well established that persistent nonsynaptic neuronal plasticity occurs after learning and, like synaptic plasticity, it can be the substrate for long-term memory. What still remains unclear, though, is how nonsynaptic plasticity contributes to the altered neural network properties on which memory depends.
Ildikó Kemenes, Volko A. Straub, Е. С. Никитин, Kevin Staras, Michael O’Shea, György Kemenes, Paul R. Benjamin   +6 more
semanticscholar   +5 more sources

Differential Roles of Nonsynaptic and Synaptic Plasticity in Operant Reward Learning-Induced Compulsive Behavior [PDF]

Current Biology, 2014
Rewarding stimuli in associative learning can transform the irregularly and infrequently generated motor patterns underlying motivated behaviors into output for accelerated and stereotyped repetitive action. This transition to compulsive behavioral expression is associated with modified synaptic and membrane properties of central neurons, but ...
Fred Sieling, Alexis Bédécarrats, John Simmers, Astrid A. Prinz, Romuald Nargeot   +4 more
semanticscholar   +4 more sources

Possible role of receptor plasticity and of nonsynaptic diffusion neurotransmission (NDN) in shoulder-hand and autonomic dysreflexia syndromes

Journal of Rehabilitation Medicine, 1994
No abstract available.
P. Bach-y-Rita
semanticscholar   +7 more sources

Nonsynaptic plasticity model of long-term memory engrams

Journal of Integrative Neuroscience, 2017
Using steady-state electrical properties of non-ohmic dendrite based on cable theory, we derive electrotonic potentials that do not change over time and are localized in space. We hypothesize that clusters of such stationary, local and permanent pulses are the electrical signatures of enduring memories which are imprinted through nonsynaptic plasticity,
L. A. Cacha, Junaid Ali, Zuhaib Haider, P. Yupapin, Roman R. Poznański   +4 more
semanticscholar   +5 more sources