Results 11 to 20 of about 265,561 (113)

Differential Roles of Nonsynaptic and Synaptic Plasticity in Operant Reward Learning-Induced Compulsive Behavior [PDF]

open access: bronzeCurrent Biology, 2014
Fred Sieling   +4 more
openalex   +2 more sources

Nonsynaptic NMDA Receptors Mediate Activity-Dependent Plasticity of Gap Junctional Coupling in the AII Amacrine Cell Network [PDF]

open access: bronzeJournal of Neuroscience, 2012
Many neurons are coupled by electrical synapses into networks that have emergent properties. In the retina, coupling in these networks is dynamically regulated by changes in background illumination, optimizing signal integration for the visual ...
W. Wade Kothmann   +5 more
openalex   +2 more sources

Role of Delayed Nonsynaptic Neuronal Plasticity in Long-Term Associative Memory [PDF]

open access: bronzeCurrent Biology, 2006
Ildikó Kemenes   +6 more
openalex   +2 more sources

WONOEP XVII appraisal: Targeting network excitability beyond the synapse -Neurotransmitter, ionic, and electro -diffusions. [PDF]

open access: yesEpilepsia
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Magloire V   +9 more
europepmc   +2 more sources

Boosting Psychotherapy With Noninvasive Brain Stimulation: The Whys and Wherefores of Modulating Neural Plasticity to Promote Therapeutic Change. [PDF]

open access: yesNeural Plast
The phenomenon of neural plasticity pertains to the intrinsic capacity of neurons to undergo structural and functional reconfiguration through learning and experiential interaction with the environment. These changes could manifest themselves not only as a consequence of various life experiences but also following therapeutic interventions, including ...
Saccenti D   +8 more
europepmc   +2 more sources

Synaptic and Non-Synaptic Functions of PTPRD: A Receptor Tyrosine Phosphatase at the Crossroads of Neural Circuitry and Metabolism. [PDF]

open access: yesJ Neurochem
PTPRD (receptor‐type protein tyrosine phosphatase delta) translates extracellular adhesion “codes” into intracellular phosphotyrosine signaling that shapes brain circuits. Alternative inclusion of micro‐exons meA and meB sculpts PTPRD's Ig domain, dictating trans‐synaptic binding to partners such as IL1RAPL1 or IL1RAP and thereby tuning synapse ...
Kim S, Shin JJ, Kang M, Yi Y, Kim E.
europepmc   +2 more sources

Rapid Ultrastructural Changes in the PSD and Surrounding Membrane after Induction of Structural LTP in Single Dendritic Spines. [PDF]

open access: yesJ Neurosci, 2021
The structural plasticity of dendritic spines is considered to be an important basis of synaptic plasticity, learning, and memory. Here, we induced input-specific structural LTP (sLTP) in single dendritic spines in organotypic hippocampal slices from ...
Sun Y, Smirnov M, Kamasawa N, Yasuda R.
europepmc   +2 more sources

A Synapse-Threshold Synergistic Learning Approach for Spiking Neural Networks [PDF]

open access: yesIEEE Transactions on Cognitive and Developmental Systems, 2022
Spiking neural networks (SNNs) have demonstrated excellent capabilities in various intelligent scenarios. Most existing methods for training SNNs are based on the concept of synaptic plasticity; however, learning in the realistic brain also utilizes ...
Hongze Sun   +6 more
semanticscholar   +1 more source

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