Results 31 to 40 of about 270,619 (156)

Effect of modulating glutamate signaling on myelinating oligodendrocytes and their development—A study in the zebrafish model

Journal of Neuroscience Research, Volume 99, Issue 11, Page 2774-2792, November 2021., 2021
Abstract Myelination is crucial for the development and maintenance of axonal integrity, especially fast axonal action potential conduction. There is increasing evidence that glutamate signaling and release through neuronal activity modulates the myelination process.
Funda Turan, Öznur Yilmaz, Lena Schünemann, Tobias T. Lindenberg, Jeshurun C. Kalanithy, Alexander Harder, Shiva Ahmadi, Türker Duman, Ryan B. MacDonald, Dominic Winter, Changsheng Liu, Benjamin Odermatt   +11 more
wiley   +1 more source

The Key Genes Underlying Pathophysiology Association between Plaque Instability and Progression of Myocardial Infarction

Disease Markers, Volume 2021, Issue 1, 2021., 2021
Young patients with type 2 diabetes and myocardial infarction (MI) have higher long‐term all‐cause and cardiovascular mortality. In addition, the observed increased, mildly abnormal baseline lipid levels, but not lipid variability, are associated with an increased risk of atherosclerotic cardiovascular disease events, particularly MI.
Yue Zheng, Yijie Gong, Yuheng Lang, Zhenchang Qi, Xiaomin Hu, Tong Li, Serena Del Turco   +6 more
wiley   +1 more source

Non-synaptic Plasticity in Leech Touch Cells

Frontiers in Physiology, 2019
The role of Na+/K+-pumps in activity-dependent synaptic plasticity has been described in both vertebrates and invertebrates. Here, we provide evidence that the Na+/K+-pump is also involved in activity-dependent non-synaptic cellular plasticity in leech ...
Sonja Meiser, Go Ashida, Go Ashida, Jutta Kretzberg, Jutta Kretzberg   +4 more
doaj   +1 more source

Reversal of age-related learning deficiency by the vertebrate PACAP and IGF-1 in a novel invertebrate model of aging: the pond snail (Lymnaea Stagnalis) [PDF]

, 2014
With the increase of life span, nonpathological age-related memory decline is affecting an increasing number of people. However, there is evidence that age-associated memory impairment only suspends, rather than irreversibly extinguishes, the intrinsic ...
Alexander, Audesirk, Chaudhury, D. Regl di, Delcourt, Du, G. Kemenes, Hattiangady, Hermann, Hernadi, I. Kemenes, J  zsa, Kemenes, Kemenes, Lee, Markowska, Otto, Otto, Patel, Patel, Pavlopoulos, Pirger, Pirger, Pirger, Roberto, S. Naskar, Sacchetti, Shioda, Silhol, Tamas, Telegdy, Vaudry, Watson, Watson, Yang, Yeoman, Z. Laszlo, Z. Pirger, Zhang   +38 more
core   +2 more sources

Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]

, 2020
Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S., Cardarelli, S., D'angelo, V., Fusco, F. R., Giorgi, M., Mercuri, N. B., Paldino, E., Sancesario, G., Sorge, R.   +8 more
core   +1 more source

Neuroinflammation: An Integrating Overview of Reactive‐Neuroimmune Cell Interactions in Health and Disease

Mediators of Inflammation, Volume 2021, Issue 1, 2021., 2021
The concept of central nervous system (CNS) inflammation has evolved over the last decades. Neuroinflammation is the response of reactive CNS components to altered homeostasis, regardless of the cause to be endogenous or exogenous. Neurological diseases, whether traumatic, neoplastic, ischemic, metabolic, toxic, infectious, autoimmune, developmental ...
Rodolfo Kölliker-Frers, Lucas Udovin, Matilde Otero-Losada, Tamara Kobiec, María Inés Herrera, Jorge Palacios, Gabriela Razzitte, Francisco Capani, Mirella Giovarelli   +8 more
wiley   +1 more source

Synergistic excitability plasticity in cerebellar functioning

The FEBS Journal, 2020
The cerebellum, a universal processor for sensory acquisition and internal models, and its association with synaptic and nonsynaptic plasticity have been envisioned as the biological correlates of learning, perception, and even thought.
G. Ohtsuki, Maria Shishikura, Akitoshi Ozaki   +2 more
semanticscholar   +1 more source

Habituation of the C-start response in larval zebrafish exhibits several distinct phases and sensitivity to NMDA receptor blockade. [PDF]

, 2011
The zebrafish larva has been a valuable model system for genetic and molecular studies of development. More recently, biologists have begun to exploit the surprisingly rich behavioral repertoire of zebrafish larvae to investigate behavior.
Dearinger, Amanda D, Esdin, Joseph, Glanzman, David L, Lu, Elaine D, Moridzadeh, Naseem, Pearce, Kaycey, Reichl, Jun, Roberts, Adam C, Song, Monica Y   +8 more
core   +3 more sources

Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult Hippocampus. [PDF]

, 2015
Cellular edema (cell swelling) is a principal component of numerous brain disorders including ischemia, cortical spreading depression, hyponatremia, and epilepsy.
Binder, Devin K, Davila, David, Fiacco, Todd A, Lauderdale, Kelli, Murphy, Thomas, Tung, Tina   +5 more
core   +3 more sources

About a snail, a toad and rodents: animal models for adaptation research

Frontiers in Endocrinology, 2010
Neural adaptation mechanisms have many similarities throughout the animal kingdom, enabling to study fundamentals of human adaptation in selected animal models with experimental approaches that are impossible to apply in man.
Eric W Roubos, Bruce G. Jenks, Lu eXu, Miyuki eKuribara, Wim J. J. M. Scheenen, Tamas eKozicz   +5 more
doaj   +1 more source