Results 51 to 60 of about 270,619 (156)

The role of astrocytes from synaptic to non-synaptic plasticity

Frontiers in Cellular Neuroscience
Information storage and transfer in the brain require a high computational power. Neuronal network display various local or global mechanisms to allow information storage and transfer in the brain.
Rafael Sanz-Gálvez, Rafael Sanz-Gálvez, Dominic Falardeau, Dominic Falardeau, Arlette Kolta, Arlette Kolta, Arlette Kolta, Yanis Inglebert, Yanis Inglebert   +8 more
doaj   +1 more source

Intrinsic plasticity complements long-term potentiation in parallel fiber input gain control in cerebellar Purkinje cells [PDF]

, 2010
Synaptic gain control and information storage in neural networks are mediated by alterations in synaptic transmission, such as in long-term potentiation (LTP).
Belmeguenai, Amor, Bengtsson, Fredrik,, De Jeu, Marcel T. G., De Zeeuw, Chris I., Elgersma, Ype, Hansel, Christian, He, Qionger, Hosy, Eric, Jörntell, Henrik,, Lund University., Lund University., Ohtsuki, Gen, Pedroarena, Christine M., Piochon, Claire, Teuling, Eva   +14 more
core   +4 more sources

A Mechanism for Ca2+/Calmodulin-Dependent Protein Kinase II Clustering at Synaptic and Nonsynaptic Sites Based on Self-Association

Journal of Neuroscience, 2005
The activity of Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays an integral role in regulating synaptic development and plasticity. We designed a live-cell-imaging approach to monitor an activity-dependent clustering of green fluorescent ...
A. Hudmon, Eric Lebel, H. Roy, A. Sik, H. Schulman, M. Waxham, P. De Koninck   +6 more
semanticscholar   +1 more source

Ultrastructural Distribution of the 7 Nicotinic Acetylcholine Receptor Subunit in Rat Hippocampus [PDF]

, 2001
Acetylcholine (ACh) is an important neurotransmitter in the mammalian brain; it is implicated in arousal, learning, and other cognitive functions. Recent studies indicate that nicotinic receptors contribute to these cholinergic effects, in addition to ...
Alan Fine, Emanuele Sher, Heather A. Davies, Michael G. Stewart, Mick L. Errington, Paul Skehel, Ruth Fabian-Fine   +6 more
core   +1 more source

Proactive and retroactive interference with associative memory consolidation in the snail Lymnaea is time and circuit dependent [PDF]

, 2019
Interference-based forgetting occurs when new information acquired either before or after a learning event attenuates memory expression (proactive and retroactive interference, respectively).
Benjamin, Paul R, Crossley, Michael, Kemenes, György, Kemenes, Ildikó, Lorenzetti, Frederick D, Naskar, Souvik, O'Shea, Michael   +6 more
core   +2 more sources

Translational Remodeling of the Synaptic Proteome During Aging

Aging Cell, Volume 24, Issue 12, December 2025.
Aging induces a decoupling of protein regulation between the soma and the synapse. In particular, transcripts coding for ribosomal proteins decrease and their corresponding proteins increase in the synapse while the opposite happens in the soma. At the same time, synapse‐specific regulation of splicing takes place.
Cinzia Caterino, Martino Ugolini, William Durso, Kristina Jevdokimenko, Marco Groth, Konstantin Riege, Matthias Görlach, Eugenio Fornasiero, Alessandro Ori, Steve Hoffmann, Alessandro Cellerino   +10 more
wiley   +1 more source

Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia. [PDF]

, 2014
Long-term memory (LTM) is believed to be stored in the brain as changes in synaptic connections. Here, we show that LTM storage and synaptic change can be dissociated.
Cai, Diancai, Chen, Shanping, Glanzman, David L, Pearce, Kaycey, Roberts, Adam C, Sun, Philip Y-W   +5 more
core   +2 more sources

Stabilization of axon branch dynamics by synaptic maturation [PDF]

, 2006
The developmental refinement of topographic projections in the brain is reflected in the dynamic sculpting of axonal arbors that takes place as connections between CNS structures form and mature.
Cline, H. T., Li, J., Ruthazer, E. S.
core   +1 more source

Anterograde Signalling by Nitric Oxide: Characterisation and In Vitro Reconstitution of an Identified Nitrergic Synapse [PDF]

, 1998
Nitric oxide (NO) is recognized as a signaling molecule in the CNS where it is a candidate retrograde neurotransmitter. Here we provide direct evidence that NO mediates slow excitatory anterograde transmission between the NO synthase (NOS)-expressing B2 ...
O'Shea, Michael, Park, Ji-Ho, Straub, Volko A   +2 more
core   +1 more source

STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs [PDF]

, 2015
STIMs (STIM1 and STIM2 in mammals) are transmembrane proteins that reside in the endoplasmic reticulum (ER) and regulate store-operated Ca2+ entry (SOCE).
Banke TG, Bardo S, Berna-Erro A, Bird GS, Bo Lu, Bourne JN, Bouron A, Brandman O, Carr DW, Colledge M, Collins SR, Cotman CW, Cotman CW, Derkach V, Diering GH, Ehlers MD, Esteban JA, Fagan KA, Fang Ji, Feske S, Finch EA, Fivaz M, Garaschuk O, Garcia-Lopez P, Gemes G, George J. Augustine, Giordano F, Gisela Garcia-Alvarez, Gogolla N, Gruszczynska-Biegala J, Hahn CG, Hama H, Hartmann J, Hawkins BJ, Hoshi N, Hu H, Huganir RL, James J. Mancuso, Jervis Vermal Thevathasan, Kaech S, Kenrick An Fu Yap, Kia Wee Tan, Krapivinsky G, Lalonde J, Lauri SE, Lee HK, Lee HK, Lefkimmiatis K, Liou J, Longair MH, Loo Chin Wong, Lu W, Lu Y, Lynette Lim, Makino H, Makino Y, Man HY, Marc Fivaz, Matsuzaki M, Mattson MP, Miesenbock G, Oh MC, Otmakhov N, Palmer AE, Park CY, Park CY, Park M, Paul Forscher, Penn AC, Porter KR, Putney JW, Rodriguez A, Roos J, Rosenbluth J, Shou Yu Poon, Skibinska-Kijek A, Skroblin P, Smith KE, Spacek J, Sun S, Tian G, Tiscornia G, Vig M, Wang X, Wang Y, Willcyn Tang, Wong LC, Wu MM, Xiao B, Yuste R, Zhang SL   +90 more
core   +1 more source