Results 51 to 60 of about 151,746 (212)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Inhaled Nanomedicines for Lung Diseases and Injuries: Pharmacological Advances and Clinical Translation

MedComm, Volume 7, Issue 11, November 2026.
Graphical overview of bioinspired regenerative platforms designed to remodel the diseased lung microenvironment. These systems integrate gene addition, siRNA‐mediated transcript silencing, CRISPR‐based modulation, and base editing approaches to promote alveolar repair, AT2‐to‐AT1 regeneration, resolution of inflammation, and restoration of vascular ...
Kajal Kamra, Sonal Gaur, Jaswinder Singh
wiley   +1 more source

Isolamento e identificação de micobactérias não-tuberculosas em laboratório e hospital de referência do Estado de Santa Catarina [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaIntrodução: O gênero Mycobacterium compreende mais de 150 espécies, incluindo patogênicas, oportunistas e não patogênicas ...
Wildner, Letícia Muraro
core  

Environmental Drivers of Nontuberculous Mycobacteria in Tropical Freshwater Systems

Environmental Microbiology, Volume 28, Issue 11, November 2026.
In tropical freshwater ecosystems, nontuberculous mycobacterial diversity and distribution is mainly driven by habitat and sample type, and local environmental factors such as sediment texture and depth. These findings highlight the importance of microhabitat conditions over broad biogeographic patterns in shaping mycobacterial communities.
Marine Combe, Amar Bouam, Sylvestre Dizoe, Bernard Davoust, Emilien Drancourt, Dylan Messeca, Alice Valentini, Romain Blaizot, Rodolphe Elie Gozlan   +8 more
wiley   +1 more source

[Nontuberculous Mycobacterium pulmonary infection with pleural effusion caused by Mycobacterium kansasii].

Kekkaku : [Tuberculosis], 1993
A 28 year-old man was admitted to our hospital because of fever, cough and chest pain. A chest X-ray film taken on admission showed infiltrate in the left upper lung field with ipsilateral pleural effusion. Microscopical examinations of stained specimens of sputa and pleural effusions disclosed no acid-fast bacilli.
IGARI, Hidetoshi, Kikuchi, Norio
openaire   +2 more sources

Comparison of patients with isolates of Mycobacterium tuberculosis and those with nontuberculous mycobacteria, Shanghai, 2008–2012.

, 2014
Abbreviations: TB, tuberculosis; NTM, nontuberculous mycobacteria; OR, odds ratio; CI, confidence interval.*P value for trend.†Adjusted variables are shown in the table.Comparison of patients with isolates of Mycobacterium tuberculosis and those with ...
Yangyi Zhang (646040), Lili Wang (104605), Xin Shen (108948), Jing Li (10611), Senlin Lin (646041), Jie Wu (10038), Qichao Pan (296550), Yuan Jiang (296541)   +7 more
core   +1 more source

Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence

mSystems, 2021
Mycobacteria are naturally resilient, and mycobacterial infections are notoriously difficult to treat with antibiotics, with biofilm formation being the main factor complicating the successful treatment of tuberculosis (TB).
Kirsi Savijoki, Henna Myllymäki, Hanna Luukinen, Lauri Paulamäki, Leena-Maija Vanha-aho, Aleksandra Svorjova, Ilkka Miettinen, Adyary Fallarero, Teemu O. Ihalainen, Jari Yli-Kauhaluoma, Tuula A. Nyman, Mataleena Parikka   +11 more
doaj   +1 more source

Synthesis, Characterization, and In Vitro Evaluation of New Amino‐Alcohol Quinolines as Promising Antimycobacterial Agents

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
Nontuberculous mycobacteria (NTM) mainly Mycobacterium avium complex (MAC), are emerging pathogens responsible for pulmonary infections. The efficacy of the standard treatment is therefore compromised by the emergence of intrinsic and acquired resistance in MAC.
Elise Si Ahmed Charrier, François Peltier, Jean‐François Raimbert, Marie Perret, Claire Andréjak, Alexandra Dassonville‐Klimpt, Pascal Sonnet   +6 more
wiley   +1 more source

Abdominopelvic Tuberculosis Secondary to a Nontuberculous Mycobacterium in an Immunocompetent Patient

Case Reports in Medicine, 2017
Tuberculosis (TB) remained as one of the top 10 causes of death worldwide despite an overall decline in its incidence rate globally. Extrapulmonary TB is uncommon and only accounts for 10–20% of overall TB disease burden. Abdominopelvic TB is the sixth most common location of extrapulmonary TB. The symptoms and signs are often insidious and nonspecific.
Beng Kwang Ng, Kembang Aziah Yakob, Wendy Yin Ling Ng, Pei Shan Lim, Raha Abdul Rahman, Abdul Karim, Ani Amelia Zainuddin, Zaleha Abdullah Mahdy   +7 more
openaire   +3 more sources