Results 61 to 70 of about 123,729 (220)

Studies on in vitro human T cell reactivity to antigens of mycobacterium tuberculosis [PDF]

, 2010
Studies on Mycobacterium tuberculosis (MTB) antigens are important to improve immunodiagnostics and vaccine efficacy. A novel genome based strategy for antigen discovery is to relate what is highly expressed by bacilli in vivo or in vitro, to what is ...
Gideon, Hannah Priyadarshini
core   +1 more source

Abdominopelvic Tuberculosis Secondary to a Nontuberculous Mycobacterium in an Immunocompetent Patient

Case Reports in Medicine, 2017
Tuberculosis (TB) remained as one of the top 10 causes of death worldwide despite an overall decline in its incidence rate globally. Extrapulmonary TB is uncommon and only accounts for 10–20% of overall TB disease burden. Abdominopelvic TB is the sixth most common location of extrapulmonary TB. The symptoms and signs are often insidious and nonspecific.
Beng Kwang Ng, Kembang Aziah Yakob, Wendy Yin Ling Ng, Pei Shan Lim, Raha Abdul Rahman, Abdul Karim, Ani Amelia Zainuddin, Zaleha Abdullah Mahdy   +7 more
openaire   +3 more sources

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target [PDF]

, 2014
The human pathogen Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis (TB), a disease with high worldwide mortality rates. Current treatment programs are under significant threat from multi-drug and extensively-drug resistant ...
VijayaShankar Nataraj, Reynolds Robert C., Nicholas J Loman, Lloyd, AJ, Besra, Gurdyal S., Klaus Fütterer, Ballell, L, Reynolds, Robert C., Abrahams, Katherine A, Loman, Nicholas J., Hobrath Judith V., Gurcha Sudagar S., Alderwick, LJ, Abrahams, Katherine A., Gurcha, SS, Cox, Jonathan A G, Abrahams Katherine A., Hobrath, JV, Loman, Nicholas J, Carlos Alemparte, Lluis Ballell, Bhatt, Apoorva; id_orcid, Cox Jonathan A. G., Loman, NJ, Besra, GS, Reynolds, Robert C, Alemparte Carlos, Alderwick, Luke J, Gurcha, Sudagar S, Besra, Gurdyal S; id_orcid, Abrahams, KA, Besra Gurdyal S., Hobrath, Judith V, Barros, D, Robert C Reynolds, Loman Nicholas J., Bhatt, A, Ballell, Lluis, Nataraj, VijayaShankar, Lloyd, Adrian J., Apoorva Bhatt, Bhatt Apoorva, Nataraj, V, Alemparte, Carlos, Lloyd, Adrian J, Fütterer, K, Hobrath, Judith V., Veeraraghavan Usha, Cox, Jonathan A. G., Cox, JA, Barros David, Veeraraghavan, Usha, Bhatt, Apoorva, Adrian J Lloyd, Jonathan A G Cox, Usha, V, Gurdyal S Besra, David Barros, Lloyd Adrian J., Reynolds, RC, Alderwick, Luke J., Ballell Lluis, Usha Veeraraghavan, Fütterer Klaus, Barros, David, Nataraj, Vijaya-Shankar, Luke J Alderwick, Gurcha, Sudagar S., Alderwick Luke J., Judith V Hobrath, Sudagar S Gurcha, Usha, Veeraraghavan, Nataraj VijayaShankar, Alemparte, C, Fütterer, Klaus, Katherine A Abrahams   +75 more
core   +1 more source

Mechanisms of Resistance, Insights From Case Reports, and Future Prospects in Mycobacteriophage Therapy

Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf, Abdul Malik, Md Shah Alam, Lijie Li, Haftay Abraha Tadesse, Aweke Mulu Belachew, Cuiting Fang, Xirong Tian, Htin Lin Aung, Shuai Wang, Tianyu Zhang   +10 more
wiley   +1 more source

Nontuberculous mycobacteria peri-prosthetic joint infection: An outcome analysis for two stage revision arthroplasty

Journal of Orthopaedic Surgery, 2022
Purpose Nontuberculous mycobacteria periprosthetic joint infection (NTMPJI) is a rare complication of hip or knee joint arthroplasty. The experience for outcomes of NTMPJI treatment is still limited.
Shih-Hui Peng, Sheng-Hsun Lee, Chun-Chieh Chen, Yu-Chih Lin, Yuhan Chang, Pang-Hsin Hsieh, Hsin-Nung Shih, Steve W N Ueng, Chih-Hsiang Chang   +8 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, Volume 16, Issue 7, Page 1271-1292, July 2026.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Antimycobacterial Activity of Laurinterol and Aplysin from Laurencia johnstonii

Marine Drugs, 2020
Marine environments represent a great opportunity for the discovery of compounds with a wide spectrum of bioactive properties. Due to their large variety and functions derived from natural selection, marine natural products may allow the identification ...
Sara García-Davis, Karla Leal-López, Carmen A. Molina-Torres, Lucio Vera-Cabrera, Ana R. Díaz-Marrero, José J. Fernández, Pilar Carranza-Rosales, Ezequiel Viveros-Valdez   +7 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, Volume 16, Issue 7, Page 1244-1258, July 2026.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Clinicopathologic Characteristics of Nontuberculous Mycobacterial Lung Disease in Taiwan

, 2011
Taiwan is an endemic area for tuberculosis (TB), and the incidence of pulmonary infection caused by nontuberculous mycobacteria (NTMs) is also increasing.
HSIAO, CHENG-HSIANG;LIN, YI-TING;LAI, CHIH -CHENG;HSUEH, PO-REN, 蕭正祥;林怡婷;賴志政;薛博仁   +1 more
core   +1 more source

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis [PDF]

, 2007
BACKGROUND: Mycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including primates. Humans are exposed through milk and from sources of environmental contamination.
Gilbert, SC, Richard Linedale, Hermon-Taylor John, Bull, TJ, Bull Tim J., Linedale Richard, Karim Sidi-Boumedine, Tim J Bull, John Hermon-Taylor, Linedale, R, Gilbert Sarah C., Gilbert, Sarah, Sidi-Boumedine Karim, Hermon-Taylor, J, Saranya Sridhar, Dierkes Nicola, Nicola Dierkes, Sridhar, S, Dierkes, N, Sidi-Boumedine, K, Sridhar Saranya, Sarah C Gilbert   +21 more
core   +1 more source