Results 81 to 90 of about 13,291 (219)

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

Acta Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami, Domenico Marson, Eiki Yamashita, Bruno Broshka, Ui Okada, Maho Aoki, Giannamaria Annunziato, Erik Laurini, Emanuele Carosati, Marco Pieroni   +9 more
wiley   +1 more source

Mycobacterium agri Skin Infection in a Previously Healthy Patient: A Case Study

Infection and Drug Resistance, 2021
Chengan Xu,1,2 Wenhao Wu,2 Hongyi Pan,3 Tianchen Hui,2 Qingqing Wu,2 Zhewen Zhou,2 Shouhao Wang,2 Wei Zheng,2 Qiaoqiao Yi,2 Hongying Pan2 1The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s ...
Xu C, Wu W, Pan H, Hui T, Wu Q, Zhou Z, Wang S, Zheng W, Yi Q, Pan H   +9 more
doaj  

A hidden threat: a case of relapsed disseminated Mycobacterium abscessus infection and its therapeutic challenges [PDF]

Journal of Bone and Joint Infection
Mycobacterium abscessus (M. abscessus) is a rapidly growing nontuberculous mycobacterium (NTM). We present the case of a 57-year-old female on immunosuppressive therapy for polymyalgia rheumatica (PMR) who developed disseminated M.
K. G. Egan, L. Duffy, C. Fleming, P. McGettrick, P. McGettrick, E. G. Muldoon, E. G. Muldoon, C. Kelly, C. Kelly, J. Woo, J. Woo, E. Kilbride, J. Butler, R. Storey, C. Quinlan, C. Quinlan, E. McDermott, J. Hunter, C. Mejia-Chew, C. Mejia-Chew   +19 more
doaj   +1 more source

Mycobacterium chubuense hand infection

IDCases, 2020
Mycobacterium chubuense is a scotochromogenic rapidly growing mycobacterium (RGM), a nontuberculous mycobacterium (NTM)that was first characterized in 1981. This case report describes a rare case of M.
Jian Ruan, Xue-Yuan Li, Hong Chen
doaj   +1 more source

Nontuberculous Mycobacterium Arthritis and Spondylitis in a Patient with Lupus

Journal of Rheumatic Diseases, 2016
Approximately 90% of nontuberculous mycobacterium (NTM) infections involve the pulmonary system; NTM infections involving areas of the musculoskeletal system such as the joints or spine are uncommon. This report describes a case of refractory knee swelling in a patient with systemic lupus erythematosus (SLE).
Nayoung Park, Sunjoo Lee, Chisook Moon, Dongyook Kim, Heuichul Gwak, Minyoung Her   +5 more
openaire   +1 more source

Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium [PDF]

Science, 2016
Global spread of aggressive mycobacteria Many mycobacteria, in addition to those causing leprosy and tuberculosis, are capable of infecting humans. Some can be particularly dangerous in patients suffering from immunosuppression or chronic disease, such as cystic fibrosis (CF). Bryant et al.
Bryant, JM, Grogono, DM, Rodriguez-Rincon, D, Everall, I, Brown, KP, Moreno, P, Verma, D, Hill, E, Drijkoningen, J, Gilligan, P, Esther, CR, Noone, PG, Giddings, O, Bell, SC, Thomson, R, Wainwright, CE, Coulter, C, Pandey, S, Wood, ME, Stockwell, RE, Ramsay, KA, Sherrard, LJ, Kidd, TJ, Jabbour, N, Johnson, GR, Knibbs, LD, Morawska, L, Sly, PD, Jones, A, Bilton, D, Laurenson, I, Ruddy, M, Bourke, S, Bowler, ICJW, Chapman, SJ, Clayton, A, Cullen, M, Dempsey, O, Denton, M, Desai, M, Drew, RJ, Edenborough, F, Evans, J, Folb, J, Daniels, T, Humphrey, H, Isalska, B, Jensen-Fangel, S, Jönsson, B, Jones, AM, Katzenstein, TL, Lillebaek, T, MacGregor, G, Mayell, S, Millar, M, Modha, D, Nash, EF, O'Brien, C, O'Brien, D, Ohri, C, Pao, CS, Peckham, D, Perrin, F, Perry, A, Pressler, T, Prtak, L, Qvist, T, Robb, A, Rodgers, H, Schaffer, K, Shafi, N, Van Ingen, J, Walshaw, M, Watson, D, West, N, Whitehouse, J, Haworth, CS, Harris, SR, Ordway, D, Parkhill, J, Andres Floto, R   +80 more
openaire   +10 more sources

The Role of Nontuberculous Mycobacteria in Patients With Cystic Fibrosis Advanced Lung Disease

Transplant Infectious Disease, Volume 28, Issue 3, May/June 2026.
Among 270 cystic fibrosis patients, 20.7% were NTM‐positive and had a lower pre‐transplant risk of death or lung transplantation but higher post‐transplant mortality, with no difference in CLAD incidence. These results suggest NTM infection should not be an absolute contraindication to lung transplantation, though careful individual risk assessment is ...
Shirin Barcikowski, Ribal Bou Mjahed, Oriol Manuel, Macé M. Schuurmans, Adrian Alonso, Zisis Balmpouzis, Jesica Mazza‐Stalder, Angela Koutsokera, Nicolas J. Mueller   +8 more
wiley   +1 more source

Diagnostic Yield of Bronchoscopy for Pulmonary Nontuberculous Mycobacterium

, 2020
St.
Tomishima, Yutaka
core  

Shedding light on Mycobacterium chelonae and its cutaneous intrusion: A case report

Journal of Microbiology and Infectious Diseases
Background: Mycobacterium chelonae, a rapidly proliferating nontuberculous mycobacterium, is renowned for instigating diverse infections, notably those affecting the integumentary system. Despite its pervasive presence in the environment, its propensity
Shankar Lal, Afreen Siddiqui, Lamis Ibrahim, Dima Youssef   +3 more
doaj   +1 more source

Mycobacterium iranicum septic arthritis and tenosynovitis

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2017
Mycobacterium iranicum is a newly reported nontuberculous mycobacterial (NTM) species that has been previously isolated in twelve patients. Our report presents the thirteenth known case of M.
Eugene M. Tan, Aaron J. Tande, Douglas R. Osmon, John W. Wilson   +3 more
doaj   +1 more source