Thermogravimetric investigation of a new intranasal gel with noopept
Recently, in the world, there is a negative dynamics of increasing diseases of the central nervous system. Creation of neuropeptide-based dosage forms with high pharmacological activity, neuroavailability and improved biopharmaceutical properties is an ...
B. S. Burlaka
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Research progress on intranasal treatment for Parkinson's disease. [PDF]
Intranasal treatment: A promising choice for Parkinson's disease (PD). Abstract Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder globally, significantly affecting the quality of life of affected individuals. Systemic drug delivery to the brain is inefficient because of first‐pass metabolism, the blood‐brain barrier (BBB),
Wen P, Ren C.
europepmc +2 more sources
The Psychonauts' World of Cognitive Enhancers. [PDF]
© 2020 Napoletano, Schifano, Corkery, Guirguis, Arillotta, Zangani and Vento. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY - https://creativecommons.org/licenses/by/4.0/).
Napoletano F +6 more
europepmc +5 more sources
Adulteration of Brain Health (Cognitive, Mood, and Sleep Enhancement) Food Supplements by the Addition of Pharmaceutical Drugs: A Comprehensive Review of Analytical Approaches and Trends. [PDF]
In recent years, the consumption of dietary supplements has grown worldwide, particularly in developed regions. However, this growing market has also become a prime target for adulteration practices, with some manufacturers illegally adding ...
Paiva R +3 more
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Study of surfactants influence on the noopept releasing from the nasal dosage form
The nasal route of drug administration, as is well known, is characterized by some advantages: absorption rate and rapid onset of therapeutic effect, availability of drug delivery without hepatic first-pass elimination, it is suitable and easily ...
B. S. Burlaka +2 more
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Borate esters: Simple catalysts for the sustainable synthesis of complex amides. [PDF]
Chemical reactions for the formation of amide bonds are among the most commonly used transformations in organic chemistry, yet they are often highly inefficient. A novel protocol for amidation using a simple borate ester catalyst is reported.
Sabatini MT, Boulton LT, Sheppard TD.
europepmc +3 more sources
Octodrine: New Questions and Challenges in Sport Supplements. [PDF]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).Background: Octodrine is the
Catalani V +9 more
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Effect of intranasal and intraperitoneal administration of peptides Semax and Noopept on the behavior of BALB/c mice [PDF]
Effects of intraperitoneal and intranasal administration of peptides noopept (1 mcg/kg/day for 5 days) and semax (0,6 mcg/ kg/day for 5 days), known to produce nootropic and anxiolytic actions were tested in BALB/c mice (the Line is characterized by ...
E. V. Vasilieva +2 more
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Protecting-Group-Free Amidation of Amino Acids using Lewis Acid Catalysts. [PDF]
Amidation of unprotected amino acids has been investigated using a variety of ‘classical“ coupling reagents, stoichiometric or catalytic group(IV) metal salts, and boron Lewis acids.
Sabatini MT +5 more
europepmc +3 more sources
The Study of [3H]-Cycloprolylglycine Pharmacokinetics in Rat Blood [PDF]
Resume. The objective of this study is to evaluate pharmacokinetic parameters of tritium-labeled cycloprolylglycine [3H] -CPG following intravenous bolus administration of 5.7 μg (2 mCi).
G. I. Kovalev +7 more
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