Results 41 to 50 of about 12,649,038 (204)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
2006 IUS Student Conference. Program and Abstracts. [PDF]
The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there were approximately 171 students displaying
2006 IU Southeast Student Conference
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Annual report of the Hampton Negro Conference [serial].
Mode of access: Internet.Continues: Hampton Negro Conference. Proceedings of the Hampton Negro Conference; earlier: Hampton Negro Conference.
Hampton Negro Conference.
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
NOR's chairman Ole K. Sara opened the conference, followed by a presentation of NOR by the secretary general Sven Skjenneberg. After he and Mauri Nieminen had presented news about reindeer research in the Nordic countries, the lectures and discussions in
Sven Skjenneberg (ed.)
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Third International Reindeer/ Caribou Symposium, Saariselkä, Finland, 1982
The third international reindeer/caribou symposium was arranged in Saariselkä, Finland, 23-26 August 1982 under the leadership of Dr. Erkki Pulliainen. 125 participants presented 70 lectures and posters.
Sven Skjenneberg
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
2009 IUS Student Conference. Abstracts. [PDF]
The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there were approximately 175 students displaying
2009 IU Southeast Student Conference
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