Results 61 to 70 of about 12,649,038 (204)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
AUSTRALIA’S PARTICIPATION AND PERFORMANCE AT THE EVIAN CONFERENCE: INTEGRITY OR SHAME?
Vestnik MGIMO-Universiteta, 2018 This article outlines and assesses the contribution made by the Commonwealth of Australia to the Evian Conference of July 1938. The attitude of the Australian government, it will be shown, was ambivalent from the start, with the Commonwealth not even ...
P. R. Bartrop
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Safety-oriented bicycling and traffic accident involvement
IATSS Research, 2018 Many U.S. bicyclists are killed or injured in traffic accidents annually. Based on analysis of available research and published reports on traffic accidents, it was theorized that adherence to six safety-oriented on-road bicycling practices will reduce ...
Mark W. Hoglund
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Biosimilars: State of Clinical and Regulatory Science
Journal of Pharmacy & Pharmaceutical Sciences, 2018 On May 12, 2017, various issues and challenges associated with biologics were discussed during a session of the annual joint conference of Canadian Society for Pharmaceutical Sciences and Canadian Chapter of Controlled Release Society at Hyatt Regency ...
Agnes Victoria Klein +3 more
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2005 IUS Student Conference. Program and Abstracts. [PDF]
, 2005 The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there were approximately 129 students displaying
2005 IU Southeast Student Conference
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
2017 IUS Student Conference. Art & Research. [Program] [PDF]
, 2017 The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there were approximately 300 students displaying
2017 IU Southeast Student Conference
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Research reports : 51st Annual Northwest Insect Management Conference
Proceedings of the 51st Northwest Insect Mamangement Conference, held January 6-7, 1992 at the Imperial Hotel in Portland ...
Northwest Insect Management Conference
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