Results 51 to 60 of about 12,649,038 (204)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

2010 IUS Student Conference. Abstracts. [PDF]

open access: yes, 2010
The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there were approximately 175 students displaying
2010 IU Southeast Student Conference
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

‘Conference’ and ‘Abbé Fétel’ pears treated with 1-methylcyclopropene: physiological and quality implications of initial low oxygen stress and controlled atmosphere storage

open access: yesAdvances in Horticultural Science, 2015
Superficial scald is a disorder developed in cold storage by ‘Conference’ and ‘Abbé Fétel’ pears and it has been related to the presence of oxidation products, mainly conjugated trienols (CTols), of which α-farnesene is primary, acting on epidermal cells.
M. Vanoli   +4 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

2019 IUS Student Conference [Program & Abstracts] [PDF]

open access: yes, 2019
The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there was a record number of students displaying
2019 IU Southeast Student Conference
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Mangoes and Eggs - A Cautionary Tale - Report from the Residential Conference on Emerging Democracies and Freedom of Information, Somerville College, Oxford, 2-4 September 1994

open access: yesInformation for Social Change, 1994
What do mangoes and eggs have to do with a library conference about emerging democracies? They emerged as symbols of capitalism and communism during the International Group of the Library Association's weekend school.
John Pateman
doaj   +1 more source

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