Results 71 to 80 of about 5,409,842 (383)

From Quinoline to Quinazoline‐Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search

open access: yesChemMedChem, 2021
Antibiotic resistance breakers, such as efflux pump inhibitors (EPIs), represent a powerful alternative to the development of new antimicrobials. Recently, by using previously described EPIs, we developed pharmacophore models able to identify inhibitors ...
Nicholas Cedraro   +13 more
semanticscholar   +1 more source

Perceptions About Asymptomatic Hyperuricemia and Views About Urate‐Lowering Therapy in People With Asymptomatic Hyperuricemia

open access: yesArthritis Care &Research, EarlyView.
Objective Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia. Methods Participants in a multinational study of
Nicola Dalbeth   +19 more
wiley   +1 more source

AAV9-cBIN1 gene therapy rescues chronic heart failure due to ischemic cardiomyopathy in a canine model

open access: yesCommunications Medicine
Background Ischemic cardiomyopathy and resultant heart failure (HF) is a significant cause of morbidity and mortality worldwide. Downregulation of cardiac bridging integrator 1 (cBIN1), a membrane scaffolding protein responsible for organizing t-tubules ...
Muhammad S. Khan   +16 more
doaj   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner   +9 more
wiley   +1 more source

Boston University Percussion Ensemble, March 27, 2017 [PDF]

open access: yes, 2017
This is the concert program of the Boston University Percussion Ensemble performance on Monday, March 27, 2017 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Chuckwalla by Roshanne Etezady, Onomatopoeia by Ramon Castillo,
School of Music, Boston University
core  

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

Chalcones Isolated from Arrabidaea brachypoda Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of Staphylococcus aureus

open access: yesAntibiotics, 2020
Bacterial resistance to antibiotics has become a public health issue around the world. The present study aimed to evaluate the antibacterial activity of chalcones isolated from flowers of Arrabidaea brachypoda, and their potential as efflux pump ...
Luis Mário Rezende-Júnior   +12 more
semanticscholar   +1 more source

Diagnostic Utility of Testing for Novel Murine Autoantibodies for Sjögren's Disease in the Rheumatology Outpatient Setting

open access: yesArthritis Care &Research, Accepted Article.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr   +5 more
wiley   +1 more source

Klimaanpassung auf regionaler Ebene: Herausforderungen einer regionalen Klimawandel-Governance

open access: yesRaumforschung und Raumordnung, 2012
The implementation of climate change adaptation strategies mainly takes part at a regional scale. This scale refers to the functional and spatial dimensions of most climate change effects.
Stefanie Baasch   +3 more
doaj   +1 more source

Heavy Quarkonium at zero and finite temperature: an effective field theory perspective

open access: yes, 2010
I discuss quarkonium physics at zero and finite temperature in the framework of nonrelativistic effective field theories.Comment: 9 pages, invited plenary talk at Chiral10, International Workshop on Chiral Symmetry in Hadrons and Nuclei, Valencia ...
Brambilla, Nora
core   +1 more source

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