Preemptive noradrenaline infusion: a game-changer against post-induction hypotension in surgical sepsis: a randomized double blind trial. [PDF]
Helmy MA +7 more
europepmc +1 more source
Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper +7 more
wiley +1 more source
Circuit-specific remodeling of synaptic co-transmission in stress-responsive networks. [PDF]
Park H, Kim H, Sim M, Ham D, Chung C.
europepmc +1 more source
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens +7 more
wiley +1 more source
Risk of antidepressant-induced hyponatremia in geriatric patients: a systematic review and meta-analysis. [PDF]
Zhang Y, Zhang J, Jing R.
europepmc +1 more source
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka +6 more
wiley +1 more source
Maintenance of maternal blood pressure targets after spinal anaesthesia for caesarean delivery: a reply. [PDF]
Chen Y, Ni X.
europepmc +1 more source
Opioid withdrawal syndrome‐associated cognitive impairment: A narrative review
Abstract Background and Objectives Opioid withdrawal syndrome (OWS) comprises a transient constellation of subjective symptoms and objective signs expressed by brain and other organs. Although cognitive impairment is well documented in opioid use and addiction, little is known about cognitive impairment that may specifically accompany OWS.
Faizan Khan +2 more
wiley +1 more source
Effect of adipose tissue insulin resistance on substrate utilization during low-intensity exercise: a pilot study in young men. [PDF]
Numao S, Uchida R, Nakagaichi M.
europepmc +1 more source
Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination
We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera +14 more
wiley +1 more source

